Reading customer reviews and comments is an excellent way to get some insider information about the exercise videos that you are interested in purchasing. These reviews are mostly given by people who have actually purchased the product in question and have given it a review and a star rating. Really pay attention to what these customers are saying. You can learn about what they liked and what they didn’t like. Even though not every customer is going to like every video they get, most people are honest about what they loved and didn’t love. Amazon is an excellent place to get these reviews and comments and check out the videos you are interested in.
Two moves is better than one, right? You may want to do this move on a mat or a towel for padding. Start in a high plank position with core tight. Lower onto both forearms at the same time, maintaining a tight core and level hips. Now push back up onto hands at the same time to return to starting position. Finish by drawing right knee into chest, then left knee into chest, doing a mountain climber.
* After you reach your peak of development, you lose muscle tissue every day up until your death. The rate at which you lose muscle tissue significantly affects how fast you "age". Strength building exercise will slow this natural loss of muscle tissue. Would you rather age quickly or slowly? What kind of shape would you prefer to be in when you're in the Fall and Winter of your life?
Want to target the upper back without a reformer? Lie face down on a mat with your feet together. Raise your head and chest slightly, and extend your arms perpendicular to your body, palms down. Exhale and sweep the arms back as you lift your chin and chest higher. Keep your waist on the mat and use your upper back muscles to bring your arms closer to your body. Return to starting position. Do five reps.
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Your body has that whole breathing thing on lock, but there's more than one way to inhale and exhale and some require extra work from the abs. "Kapalabhati breathing engages the transverse abdominis to push out the breath," says Allison Candelaria, owner of Soul Yoga in Oklahoma City. Here's how to do it: Sit tall, then strongly and quickly pull your navel toward your spine. Then release your ab muscles, forcing you to exhale. Work up to doing that 20 times, inhaling and letting your belly expand between each "pump." (This belly bonfire breathing technique can also help you fire up your body anywhere, anytime.)
The popular belief is that two training methods are needed to be physically fit: working with weight for muscle strength, and aerobics for cardiovascular fitness. This is untrue. One of the biggest jobs of the cardiopulmonary system (heart and lungs) is to service the muscles. If the cardiopulmonary system were a retail store, the muscular system would be its biggest customer. When your muscular system works harder, the cardiopulmonary system works harder; it's not the other way around. So, working your muscles hard will force the cardiopulmonary system to work hard. Muscular work of sufficient intensity requires the cardiopulmonary system to work hard to meet muscular demands, so one activity takes care of both muscular and cardiopulmonary fitness. And that activity is strength training. Think about it, you can't exercise the cardiopulmonary system without exercising the muscular system! So, although the fitness industry remains blind to the above facts, strength training will provide you with every exercise-related health benefit you could possibly want. Doing "cardio work" is a waste of time and physiological resources, and can actually be counterproductive.
Rest-Pause Sets. The body is an amazing machine, with the right amount of rest it can surprise us with its tenacity. With a weight near your 3 or 5 rep maximum, perform as many reps as possible, then re-rack. Rest for 10 to 15 seconds, then grab it again and go at it. Make sure to keep correct form, and go/rest until you can't budge the bar. Make sure to only do this once.

I've given this program a good 6 weeks so far. I'm 5-10 pounds overweight with some physical issues and a history of car crash injuries. I have a medical degree and a background in nutrition and fitness with several years of yoga (various disciplines) under my belt. Overall, I do like the program, but there are some VERY important things you should know before purchasing and participating..
Congratulations on your decision to make yourself a priority and commit to a regular workout routine. The addition of physical fitness into your life requires hard work, but yields great rewards. Now, which method should you choose? With the vast choice of fitness workout options available today, it can be overwhelming to know which one is right for you.
Anyone who watched Jackie Warner on Bravo's Work Out knows she takes a tough-love approach to fitness. And, clearly, if you've checked out her abs lately, it works. She shares her signature circuit-training workout in this high-energy DVD that gives the option of four different 15-minute workouts or one 40-minute total body circuit, and left me feeling like I just had an up-close-and-personal training session with the exercise guru. 

Major variants: incline ~ (more emphasis on the upper pectorals), decline ~ (more emphasis on the lower pectorals), narrow grip ~ (more emphasis on the triceps), push-up (face down using the body weight), neck press (with the bar over the neck, to isolate the pectorals), vertical dips (using parallel dip bars) or horizontal dips (using two benches with arms on the near bench and feet on the far bench, and dropping the buttocks to the floor and pushing back up.)
For Paced Audio Workouts: MotionTraxx (iPhone or iPad) - This music-based app is another great option for home exercisers, particularly if you're a walker or runner. Deekron the Fitness DJ has put together an incredible variety of music mixes, all set at different beats per minute, so you can find the perfect pace for any workout - Walking, running, lifting weights or other activities. There are also coached workouts (these cost extra) available at iTunes.
Jump up ^ Lees C, Hopkins J (2013). "Effect of aerobic exercise on cognition, academic achievement, and psychosocial function in children: a systematic review of randomized control trials". Prev Chronic Dis. 10: E174. doi:10.5888/pcd10.130010. PMC 3809922. PMID 24157077. This omission is relevant, given the evidence that aerobic-based physical activity generates structural changes in the brain, such as neurogenesis, angiogenesis, increased hippocampal volume, and connectivity (12,13). In children, a positive relationship between aerobic fitness, hippocampal volume, and memory has been found (12,13). ... Mental health outcomes included reduced depression and increased self-esteem, although no change was found in anxiety levels (18). ... This systematic review of the literature found that [aerobic physical activity (APA)] is positively associated with cognition, academic achievement, behavior, and psychosocial functioning outcomes. Importantly, Shephard also showed that curriculum time reassigned to APA still results in a measurable, albeit small, improvement in academic performance (24).  ... The actual aerobic-based activity does not appear to be a major factor; interventions used many different types of APA and found similar associations. In positive association studies, intensity of the aerobic activity was moderate to vigorous. The amount of time spent in APA varied significantly between studies; however, even as little as 45 minutes per week appeared to have a benefit.
Many exercise protocols are in use in clinical cardiology, but no single test is applicable to the wide range of patients' exercise capacity. A new protocol was devised that starts at a low workload and increases by 15% of the previous workload every minute. This is the first protocol to be based on exponential rather than linear increments in workload. The new protocol (standardised exponential exercise protocol, STEEP) is suitable for use on either a treadmill or a bicycle ergometer. This protocol was compared with standard protocols in 30 healthy male volunteers, each of whom performed four exercise tests: the STEEP treadmill and bicycle protocols, a modified Bruce treadmill protocol, and a 20 W/min bicycle protocol. During the two STEEP tests the subjects' oxygen consumption rose gradually and exponentially and there was close agreement between the bicycle and the treadmill protocols. A higher proportion of subjects completed the treadmill than the bicycle protocol. Submaximal heart rates were slightly higher during the bicycle test. The STEEP protocol took less time than the modified Bruce treadmill protocol, which tended to produce plateaux in oxygen consumption during the early stages. The 20 W/min bicycle protocol does not take account of subjects' body weight and consequently produced large intersubject variability in oxygen consumption. The STEEP protocol can be used on either a treadmill or a bicycle ergometer and it should be suitable for a wide range of patients.
One way repeated ANOVA was used to compare time to exhaustion between sessions (S1, S2 and S3). Relative reliability was calculated with the intraclass correlation (ICC) model (3, 1) [27]. Absolute reliability was calculated with the typical error of measurement (the standard deviation of the change scores divided by [28, 29]). Bland and Altman’s 95% limits of agreement were also used (calculated for S1 vs S2, S1 vs S3 and S2 vs S3) as an additional representation of measurement error and to identify the presence of heteroscedasticity [19]. As data were heteroscedastic, both raw data and log transformed Bland and Altman’s plots are presented. Limit of agreement ratio (LOA) was also calculated from the log transformed data as follow: LOA = (1.96 × SDdiff / grand mean) × 100; where “SDdiff” represents the SD of the differences between tests (S1 vs S2, S1 vs S3, S2 vs S3) and “grand mean” represents (mean S1 + mean S2 + mean S3)/3. As time to exhaustion data were heteroscedastic, we also calculated the coefficient of variation (CV) for each subject as follow: CV = 100×(SD of the three measurements)/(mean of the three measurements). Mean CV for all subjects were also calculated. We also calculated the smallest worthwhile change (0.2 × between subjects SD) [21].
The bench press or dumbbell bench-press is performed while lying face up on a bench, by pushing a weight away from the chest. This is a compound exercise that also involves the triceps and the front deltoids, also recruits the upper and lower back muscles, and traps. The bench press is the king of all upper body exercises and is one of the most popular chest exercises in the world. It is the final exercise in 'The big 3'.
Most people instinctively move weights very quickly - they jerk upwards, lower the weight without much control, and tense up and use momentum to "bounce" the weight at both ends of the repetition. The instinct serves a purpose - the speed and bounce at the ends do allow heavier weight to be moved. In competitive weightlifting both explosive speed and momentum are essential.
^ Jump up to: a b c Schuch FB, Vancampfort D, Rosenbaum S, Richards J, Ward PB, Stubbs B (July 2016). "Exercise improves physical and psychological quality of life in people with depression: A meta-analysis including the evaluation of control group response". Psychiatry Res. 241: 47–54. doi:10.1016/j.psychres.2016.04.054. PMID 27155287. Exercise has established efficacy as an antidepressant in people with depression. ... Exercise significantly improved physical and psychological domains and overall QoL. ... The lack of improvement among control groups reinforces the role of exercise as a treatment for depression with benefits to QoL.

After familiarization, a preliminary OLDE incremental test was performed until exhaustion to measure peak power output. For males, the incremental test started with the isotonic resistance set at 4 N·m (~ 7.4 W) for 1 min, and increased each minute by 3 N·m (~ 4.5 W) to exhaustion. For females, the isotonic resistance was set up at 4 N·m (~ 7.4 W) for 1 min and increased each minute by 2 N·m (~ 3.7 W). Exhaustion was defined as a decrease in cadence below 40 cpm for a duration ≥ 10 s or when the subject voluntarily stopped.
In her hilarious, naked, and explicitly honest anecdote, she described her aversion to most fitness regimens ("I can't run because I piss myself . . . and fart at the same time"), her DVD workout — "Charlotte's 3-Minute Belly Blitz" — and her complete surprise at the intensity of the routine ("THAT'S the f*cking WARMUP?"). To be honest, most of us have been there, so this is pretty damn relatable.
The recent “consensus statement” of the European College of Sport Science indicates that the difference between NFO and OTS is the amount of time needed for performance restoration and not the type or duration of training stress or degree of impairment.1 In essence, it is generally thought that symptoms of OTS, such as fatigue, performance decline and mood disturbances, are more severe than those of NFO. However, there is no scientific evidence to either confirm or refute this suggestion.1 The distinction between NFO and OTS is most of the time based on “time to recover”. Hence, there is a need for objective, immediately available evidence that the athlete is indeed experiencing OTS.

These small exercises may sound like a lot to remember, but you can just start one-at-a-time until each thing becomes a true habit. The trick is to associate exercises with mini-cues. Tell yourself that “If I take the elevator three floors or lazily brush my teeth without squatting, then I am missing a huge opportunity for growth.” Once you have internalized these habits and associated them with a cue, you won’t really have to think about exercising at all.  It just happens.
Squat between putting away dishes. During repetitive physical activities such as putting away dishes or loading the dishwasher, throw in squat, lunge, or other repetitive exercise between each repetition. This way, you'll naturally end up doing repetitions of exercises that need to be performed in repetition. putting each dish away or in the dishwasher.
18.  If you experience pain while working out, STOP! Although moving slowly drastically decreases the probability of injury, common sense dictates that if you feel pain, stop and try again a week later. Maybe you weren't hydrated enough, and maybe you need to reduce the resistance. And pain is not to be confused with a "burn". The expression, "No pain, no gain" is misleading. Pain is a warning to stop. A burning sensation simply means you've worked the muscle very intensely.
For this basic strength-training workout, you'll do 1 set of 15 reps of each of the nine exercises listed below, resting briefly between exercises as needed. The workout targets all the muscles in the body, including the chest, shoulders, arms, back, hips, glutes, and thighs. It's short and simple—a great way for beginners to get started with strength training. 
We have included step by step instructional guides for over 500 different resistance training exercises. This database covers a wide variety of different exercises including free weights, CrossFit, kettlebells, machines, bodyweight, medicine ball, elastic bands, exercise ball, Pilates and stretching movements. Choose from a list for a specific muscle group or select by exercise type to pick the best exercises for your workout. Each instructional page will show you how to properly perform a resistance training exercise with detailed photos and exercise advice for each movement. It’s like having your very own personal trainer. These exercise guides will help set you on the right track so you can get in the best shape of your life!
Exercise is key to good health. But we tend to limit ourselves to one or two types of activity. "People do what they enjoy, or what feels the most effective, so some aspects of exercise and fitness are ignored," says Rachel Wilson, a physical therapist at Harvard-affiliated Brigham and Women's Hospital. In reality, we should all be doing aerobics, stretching, strengthening, and balance exercises. Here, we list what you need to know about each exercise type and offer examples to try, with a doctor's okay.
The most important thing you need is you. Just grab a yoga mat, water, and towel and find a space wide enough to take a step in each direction. The PiYo 60-Day Calendar comes with the program and strategically lays out your workout schedule to keep you progressing each week as you build your strength, flexibility, and stamina. The Get Lean Eating Plan gives you a simplified approach to clean and lean eating designed to fit your lifestyle.
"Consider this: Dr. Kenneth Cooper (author of Aerobics, The New Aerobics, Aerobics for Women), the U.S. Air Force Cardiologist who coined the term 'aerobics" (meaning a form of exercise) and has promoted their use for over 25 years, now admits that he was wrong! According to Dr. Cooper, further research has shown that there is no correlation between aerobic endurance performance and health, longevity, or protection against heart disease. He will admit, however, that such activities do carry with them a great risk of injury. Further, he admits that gross-overuse activities such as running are damaging to the body." – Ken Hutchins, SuperSlow Exercise Guild
2. The "For Dummies" series. Any of the "Dummies" series videos (like Shaping up with Weights for Dummies, Pilates for Weight Loss for Dummies and Basic Yoga for Dummies) are usually excellent, says Zurowski. These videos go slowly, explain the workout clearly, and show the exercise from multiple angles. The instructor is always alone, so there are no distractions. Another good feature of this series is that it also shows mistakes to avoid, says Glenna.
For Ready-Made or Make Your Own Workouts: Fitness Builder (iPhone or iPad)- This is one of my favorite exercise apps, offering a variety of ways to exercise. You can choose workouts based on the equipment you have, the muscle groups you want to work or the type of workout you're looking for. There are a range of ready-made workouts and you can also create your own workouts from the amazing database of exercises included.
I found pound at Crunch Fitness when I lived in LA. You had to sign up for the class ahead of time and they would run out of sticks because the classes were so packed (so I ended up buying my own to bring). The live classes were much more fun than the videos, I think because of the music. At the gym, the instructors would play fun current or popular hit songs really loud. In the videos, it’s more focused on instruction than the music, even though they have options for music only –see below.

One of the main reasons I don't do Pilates very often is that, for me, it gets too boring after a while. Enter this DVD. Made up of five 10-minute workouts, it kept me engaged because I was able to change up the routine often, or, if I only had a few minutes available, I could still squeeze in a workout with just one of the programs. I just might be a Pilates convert after all.

The two 20-minute high-energy kickboxing routines combined with other cardio moves eliminate boredom in this program. When I felt particularly ambitious, I did both together for one calorie-blasting 40-minute workout; I chose one or the other when I only had 20 minutes to spare in the morning. Make sure to do this in a spacious room, because the amount of kicking, punching and movement, as I unfortunately discovered, is not tailored to tiny spaces.
The European Commission - DG EAC - Directorate General for Education and Culture - has dedicated programs and funds for HEPA - Health Enhancing Physical Activity projects[134] within its Horizon 2020 and Erasmus+ program, as research showed that too many Europeans are not physically active enough. Financing is available for increased collaboration between players active in this field across the EU and around the world, the promotion of HEPA in the EU and its partner countries and the European Sports Week. The DG EAC regularly publishes a Eurobarometer on sport and physical activity.
Drop Sets. Drop sets can be performed with any exercise that involves moving weight around, like squats or the bench press. You have performed ten bench presses and couldn't possibly do eleven. Re-rack the weight and have a partner take off ten pounds or so, then perform as many reps as possible at that new weight. It's even easier to use dumbbells and simply move to smaller and smaller bells, set to set. Three total drop sets is the norm, do this to infinity and beyond and you may be way too sore the next day.

Our method is an extremely important addition to any childbirth class or current fitness method that you love being a part of. We believe that by adding our methodology to your pregnancy, we can keep you doing what you love in the safest and most effective way possible. This method was developed with all stages of pregnancy in mind and our clients continue to see endless benefits from incorporating The Bloom Method into their regular fitness routine, for life.
Major findings: Within a few decades of the turn of the 20th century, a cluster of mind–body exercise methods emerged from at least six pioneering founders: Checkley, Müller, Alexander, Randell, Pilates, and Morris. Each was based upon a similar exercise philosophy and similar functional movement-harmonizing exercises. This renaissance of independent mind–body schools occurred in parallel with the demise of the 18th and 19th century gymnasium Physical Culture movement and the concurrent emergence of bodybuilding and strength training. Even though mostly forgotten today, Western mind–body exercise methods enjoyed celebrated success during the first half of the 20th century, were hailed by medical and allied health practitioners and practiced by millions from society’s elite to deprived minorities.
Negative Sets. Weight training works with and against gravity. The motion towards the bar in a pull-up is called the "concentric movement," while heading back towards the ground is an "eccentric movement," or the negative portion of the movement. Resisting the pull of gravity during the negative porting of the movement taxes the muscles in a different way Myofibrillar disruption following acute concentric and eccentric resistance exercise in stregth-trained men. Gibala, M.J., Interisano, S.A., Tarnopolsky, M.A., et al. Department of Kinesiology (Neurology and Neurological Rehabilitation), McMaster University, Hamilton, ON, Canada. Canadian Journal of Physiology and Pharmocology. 2000 Aug;78(8):656-61.. At the end of a long set, switch to just performing negatives (with a partner's help on the way up) or work towards getting those difficult bodyweight movements (like a pull up or dip) by only performing the negative of the movement. Sounds easy? Just try it!
The world population is ageing and the number of older adults with chronic health conditions and physical limitations is expected to increase. This, in turn, could lead to an increased burden on healthcare services [1]. Regular physical activity is an important component of successful ageing and reduces the risk of developing several age- and lifestyle related diseases such as cardiovascular disease, dementia and type 2 diabetes [2–7]. However, making older adults exercise and keeping them in exercise programs is a major challenge [8]. Understanding how older adults prefer to exercise may help developing tailored exercise programs and increase sustained exercise participation in ageing populations.
The good-morning is a weight training exercise in which a barbell, two dumbbells, or no weight at all is held on the shoulders, behind the head. The person bends forward and bows at the hips and recovers to upright. The good-morning is so called because the movement resembles bowing to greet someone. It involves the hamstrings but is primarily used to strengthen the lower back; the degree of knee bend used will change the focus – nearly straight-legged involving the hamstrings most.
Aerobic exercise induces short- and long-term effects on mood and emotional states by promoting positive affect, inhibiting negative affect, and decreasing the biological response to acute psychological stress.[45] Over the short-term, aerobic exercise functions as both an antidepressant and euphoriant,[46][47][48][49] whereas consistent exercise produces general improvements in mood and self-esteem.[50][51]
Inappropriate exercise can do more harm than good, with the definition of “inappropriate” varying according to the individual. For many activities, especially running and cycling, there are significant injuries that occur with poorly regimented exercise schedules. Injuries from accidents also remain a major concern,[85] whereas the effects of increased exposure to air pollution seem only a minor concern.[86][87]
Physiological, psychological and EMG responses to the time to exhaustion tests are presented Figs 4 and 5. Leg RPE (Fig 4A), leg muscle pain (Fig 4B) and heart rate (HR, Fig 4C) increased over time (all P < 0.001). Cadence during the time to exhaustion decreased over time (P < 0.001). Planned comparisons for these aforementioned parameters are presented Fig 5. EMG RMS of the VL (Fig 5A), VM (Fig 5B), RF (Fig 5C) and the sum of these muscles (Fig 5D) increased over time (all P < 0.001). Planned comparisons for EMG parameters are presented Fig 5. Blood lactate concentration increased (from 1.3 ± 0.5 to 6.0 ± 1.1 mmol/L, P < 0.001) and blood glucose concentration decreased (from 5.3 ± 0.5 to 4.4 ± 0.3 mmol/L, P = 0.001) over time.

If watching Dancing With the Stars inspired you to get grooving, you should definitely try this DVD for a guided shape-up. Although I suggest shutting your curtains and banishing anyone else from the house while you shake it, learning the routines kept me focused and by the end, I was sweating and laughing (at myself). Skimpy sequined outfits and B-list celebs not required.


If there’s one travel-friendly workout tool, it’s the resistance band. Not only does it weigh next to nothing and take up little room in your bag, it’s also super versatile. And if you’re a fan of our full-body resistance band workout, you’ll definitely dig this free workout video. It combines strength movements, like rear lunges with a rotation, with heart rate-boosting exercises for a routine that’ll challenge your entire body.
Lisa Avellino, Fitness Director at NY Health and Wellness, says to grab a kitchen towel and engage in just 30 seconds of isometric motion with it. “Thirty seconds of opposing pull—like a human tug-a-war—will take any muscle to its maximum potential because you use your own bodyweight as resistance,” she explains. “The best part is that the stronger you are the more challenging the workout is, so you can never surpass maximum potential.” Speaking of the kitchen, check out these 25 Ways to Organize Your Kitchen for Weight Loss!
Okay, this one if for the kids, but grown-ups can do it to too. With animated instructions, catchy music, and all the basics of the other full-body workouts, this is another top choice overall. The exercises include some more advanced moves, like tricep dips with a chair and push-ups with rotation, so it’s a great one to do with your kids.                                    

If you ask most busy people why they don’t exercise, by far the most common reason is that that they “don’t have time.” The effort of putting on workout clothes, going to the gym and showering is simply too onerous to fit in. Even the idea of a boring home workout or a 30-minute exercise tape can feel like too much of a commitment when we’re late for work or for a date.
Neuromuscular function tests were performed pre and post-exercise to quantify muscle fatigue. As previous studies documented the extent of isometric muscle fatigue induced by OLDE [8, 11, 17, 18], we chose to focus only on isokinetic muscle fatigue. Therefore, knee extensors (KE) MVCs were performed at 60 (MVC60), 100 (MVC100) and 140 (MVC140) deg/s pre (after the warm-up) and post-exercise (13 ± 4s after exhaustion). Subjects were asked to perform two maximal isokinetic knee extensions at each angular velocity (starting position corresponded to knee angle at 90 deg; range of motion was the same as the OLDE). The highest peak torque value of the two trials was considered, and a 20 s recovery was set between each set of KE MVCs. The order of contractions was randomized between sessions as follow (60-100-140 deg/s, 100-140-60 deg/s or 140-60-100 deg/s) and identical for testing pre and post-exercise of the same session. This randomization allows obtaining a time course of KE MVC torque recovery following the time to exhaustion test at each angular velocity was obtained at a different time point at each session: either shortly after exhaustion (13 ± 4 s after exhaustion), 20 s following exhaustion test (P20) and 40 s following exhaustion test (P40). An overview of timing can be found in Fig 1. Twenty seconds after completion of the last KE MVC, a maximal isometric MVC of the knee flexors was performed (isometric KF MVC). Visual feedback of the torque and strong verbal encouragement were provided for each MVC [please see reference 9 for more details].
Since almost any exercise requires some strength and some level of aerobic fitness, I recommend a training program that is a mix of both strength training and conditioning; similar to what I do but on a smaller scale (to start). The Stronglifts 5x5 workout that I mentioned above is an excellent place to start and requires only three days a week. Assuming you can exercise five days a week, you can do some aerobic/anaerobic work on Tuesdays and Thursdays. If five days a week is too much, start with a three-day strength workout. If you also want to do conditioning, you can choose to perform it after your strength routine for 10–30 minutes, or just shift your focus after a few weeks of strength training and do conditioning only for a week or two.
Ten patients who consulted a sports physician with complaints of underperformance and fatigue participated in the present study. The eight men and two women had an average height and weight of 181±(8) cm and 68.4±(11.8) kg. All subjects were diagnosed by a sports physician according to the latest guidelines for overtraining diagnosis.1 18 A careful history including training history was taken, completed by a physical examination and a blood draw to rule out other possible causes for the complaints. Patients were diagnosed as NFO or OTS retrospectively according to the severity of symptoms and the total duration of symptoms and underperformance (ie, both before and after testing) when no medical explanation for the condition could be found. It turned out that a cutoff of 1-year total duration gave a good distinction between NFO and OTS patients. Demographic data and reported symptoms can be found in table 1. Data of subject 1 are the same as presented in an earlier publication.10 All subjects signed informed consent before participation.
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