Limitation of the Study. One potential limit of the present study undoubtedly regards the limited number of subjects involved in the study and the operating loss of the control group. Unfortunately, too many participants of the latter did not satisfy the requirements during the study, thus impeding a comparative statistical approach. Further studies are therefore needed to confirm our conclusions, in particular with a larger sample and control group.
KE EMG RMS corresponds to the sum of EMG RMS of the following muscles: Vastus Lateralis, Rectus Femoris and Vastus Medialis. Isokinetic KE MVCs were performed at 60 (panel, A), 100 (panel B) and 140 (panel C) deg/s. Isokinetic KE MVCs were measured pre-exercise (pre, average of all three sessions pre-exercise values), shortly after exhaustion (13 ± 4 s after exhaustion), 20 s following exhaustion test (P20) and 40 s following exhaustion test (P40). Data are presented as mean (SE).

Leg muscle pain, defined as “the intensity of hurt that a subject feel in his quadriceps muscles only” [26], was measured during the incremental test (at the end of each minute) and during the time to exhaustion tests (at the end of the warm-up and every 30 s) using the Cook scale [26]. Standardized instructions for the scale were given to each subject before the warm-up. Briefly, subjects were asked to rate the feelings of pain specifically in their quadriceps and not to report other pains they may have experienced (e.g., seat discomfort). Subjects were also asked to not use this rating as an expression of perceived effort [24].
If you’re sick of doing endless repetitions of traditional squats, check out this video to challenge your muscles in new ways and spark some creativity. “We asked certified personal trainer and Women’s Health’s Next Fitness Star, Selena Watkins, to pull together 15 dance-inspired versions of this classic booty toner, and the results are giving us a whole new appreciation for an old-school move,” says the magazine. This routine is just a sampler of some of the squat variations you could complete. Pick three or four and incorporate them into your next leg day to spice things up.
Perception of effort, defined as “the conscious sensation of how hard, heavy, and strenuous exercise is” [23, 24], was measured during the incremental test (at the end of each minute) and during the time to exhaustion tests (at the end of the warm-up and every 30 s) using the 15 points RPE scale (Borg 1998). Standardized instructions for the scale were given to each subject before the warm-up. Briefly, subjects were asked to rate how hard they were driving their leg during the exercise (leg RPE [8, 24, 25]). Subjects were also asked to not use this rating as an expression of leg muscle pain (i.e., the intensity of hurt that a subject feels in his quadriceps muscles only).
Jump up ^ Gomez-Pinilla F, Hillman C (January 2013). "The influence of exercise on cognitive abilities". Compr. Physiol. 3 (1): 403–428. doi:10.1002/cphy.c110063. ISBN 9780470650714. PMC 3951958. PMID 23720292. Abundant research in the last decade has shown that exercise is one of the strongest promoters of neurogenesis in the brain of adult rodents (97, 102) and humans (1,61), and this has introduced the possibility that proliferating neurons could contribute to the cognitive enhancement observed with exercise. In addition to BDNF, the actions of IGF-1 and vascular endothelial growth factor (VEGF) (54) are considered essential for the angiogenic and neurogenic effects of exercise in the brain. Although the action of exercise on brain angiogenesis has been known for many years (10), it is not until recently that neurovascular adaptations in the hippocampus have been associated with cognitive function (29). Exercise enhances the proliferation of brain endothelial cells throughout the brain (113), hippocampal IGF gene expression (47), and serum levels of both IGF (178) and VEGF (63). IGF-1 and VEGF, apparently produced in the periphery, support exercise induced neurogenesis and angiogenesis, as corroborated by blocking the effects of exercise using antibodies against IGF-1 (47) or VEGF (63).

If watching Dancing With the Stars inspired you to get grooving, you should definitely try this DVD for a guided shape-up. Although I suggest shutting your curtains and banishing anyone else from the house while you shake it, learning the routines kept me focused and by the end, I was sweating and laughing (at myself). Skimpy sequined outfits and B-list celebs not required.

"CrossFit differentiates itself by being constantly varied in both movements and time domains," Mandelbaum says. "You might have a day in the box with a four-minute sprint workout one day, and then come in the next day for a 15-minute moderate-to-fast-paced workout featuring three movements that need to be repeated in a cycle or round until the time clock runs out."
If the proliferation of many websites on the subject (not to mention the co-worker who won't let you forget he does CrossFit, bro) are any indication, the first rule of CrossFit is never stop talking about CrossFit. And while this would seem to encourage certainty about what CrossFit actually is, there are a lot of myths and generalizations to clear up about the workout regimen.
Diagram of the molecular signaling cascades that are involved in myofibrillar muscle protein synthesis and mitochondrial biogenesis in response to physical exercise and specific amino acids or their derivatives (primarily l-leucine and HMB).[92] Many amino acids derived from food protein promote the activation of mTORC1 and increase protein synthesis by signaling through Rag GTPases.[92][101]
To try it, choose a medium-heavy weight (50 percent to 70 percent of your one-rep-max, or 1RM, if you know it). Lift it with as much velocity as you can muster, then lower it with control. For instance, if you are bench pressing, the push up will feel almost as though you are punching the weight up into the ceiling. Once you have completed the lift, slowly lower the weight to your chest. You can apply this technique using a variety of implements, including dumbbells, barbells, weight machines, elastic bands, and body weight, he explains.

Jump up ^ Linke SE, Ussher M (2015). "Exercise-based treatments for substance use disorders: evidence, theory, and practicality". Am J Drug Alcohol Abuse. 41 (1): 7–15. doi:10.3109/00952990.2014.976708. PMC 4831948. PMID 25397661. The limited research conducted suggests that exercise may be an effective adjunctive treatment for SUDs. In contrast to the scarce intervention trials to date, a relative abundance of literature on the theoretical and practical reasons supporting the investigation of this topic has been published. ... numerous theoretical and practical reasons support exercise-based treatments for SUDs, including psychological, behavioral, neurobiological, nearly universal safety profile, and overall positive health effects.
C. Philip Gabel is the founder and principal physiotherapist at Coolum Physiotherapy, Queensland Australia. His research interests are rehabilitation and exercise, slacklining, laser therapy, and outcome measures. His publications are Cross-cultural adaptation, reliability, and validity of the Spanish version of the lower limb functional index. Health and Quality of Life Outcomes, 2014; Analysis of arm elevation muscle activity through different movement planes and speeds during in-water and dry-land exercise. Journal of Shoulder Elbow Surgery 2014.
* Respect the body's design when exercising. We are capable of doing many things the body was not designed to do. And this is also true when it comes to physical activity. We're designed to walk, climb, and sprint. We walked a lot back in the good old days when we foraged in paradise, we climbed to get the sweetest fruit, and we occasionally sprinted to escape danger. Take a cue from little kids: they love to climb, when they run they sprint (try to get them to do distance running), and they can walk just fine. When we do the activities we're designed to do, that's when we'll be in great shape... we won't be under-active, and we won't be over-active, and both are bad for the body, for different sets of reasons.
Samples were collected in prefrozen 4.5 ml K3 EDTA vacutainer tubes (Becton Dickinson Vacutainer System Europe, Plymouth, UK) and immediately centrifuged at 3000 rpm (Minifuge 2, Heraeus, Germany) for 10 min, and plasma was frozen at −20°C until further analysis. Samples were assayed via RIA for cortisol (DiaSorin, Stillwater, Minnesota, USA), ACTH (Nichols Institute Diagnostics, San Juan Capistrano, California, USA), PRL (Roche Diagnostics, Mannheim, Germany) and GH (Pharmacia & Upjohn Diagnostics, Uppsala, Sweden).

Jump up ^ Hubal MJ, Gordish-Dressman H, Thompson PD, Price TB, Hoffman EP, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Clarkson PM; Gordish-Dressman; Thompson; Price; Hoffman; Angelopoulos; Gordon; Moyna; Pescatello; Visich; Zoeller; Seip; Clarkson (June 2005). "Variability in muscle size and strength gain after unilateral resistance training". Medicine & Science in Sports & Exercise. 37 (6): 964–972. PMID 15947721.

Notice in the workouts below that your first set calls for eight reps, your second set 10 reps and your third set 12. This is referred to in bodybuilding circles as a “reverse pyramid” (a standard pyramid goes from higher to lower reps), where you decrease the weight each set to complete the higher rep count. For example, if on your first set of lat pulldowns you used 140 pounds for eight reps, try using 120 or 130 pounds on set two and 100–120 pounds on set three.
In 1912, Alexander claimed that the principles of ‘conscious control’ constitute an unfailing remedy for disease, including the cases of shortening of the spine, an injured arm, and a golfer who is practicing his swing.21 Pilates and Alexander [Internet]. Macy JA. Alexander Technique and the Pilates method of movement re-education: A biomechanical perspective. 2010 Dec 6 [cited 2015 Aug 30]. Available from: http://pilatesandalexander.com/articles/macy/. [Google Scholar] Alexander was against weightlifting, claiming that their focus on isolating muscles did not address the short- and long-term damage of impaired functional movements: ‘The physical body thus had two existences ... one fiercely active, muscular, dynamic, the other sedentary, nervous, static.’21 Pilates and Alexander [Internet]. Macy JA. Alexander Technique and the Pilates method of movement re-education: A biomechanical perspective. 2010 Dec 6 [cited 2015 Aug 30]. Available from: http://pilatesandalexander.com/articles/macy/. [Google Scholar] He allied himself with the turn of the 20th century MMB movement emergence:20 Alexander FM. Man's supreme inheritance. London: Methuen; 1910. [Google Scholar]
A number of medical reviews have indicated that exercise has a marked and persistent antidepressant effect in humans,[37][48][49][52][70][71] an effect believed to be mediated through enhanced BDNF signaling in the brain.[40][52] Several systematic reviews have analyzed the potential for physical exercise in the treatment of depressive disorders. The 2013 Cochrane Collaboration review on physical exercise for depression noted that, based upon limited evidence, it is more effective than a control intervention and comparable to psychological or antidepressant drug therapies.[70] Three subsequent 2014 systematic reviews that included the Cochrane review in their analysis concluded with similar findings: one indicated that physical exercise is effective as an adjunct treatment (i.e., treatments that are used together) with antidepressant medication;[52] the other two indicated that physical exercise has marked antidepressant effects and recommended the inclusion of physical activity as an adjunct treatment for mild–moderate depression and mental illness in general.[48][49] One systematic review noted that yoga may be effective in alleviating symptoms of prenatal depression.[72] Another review asserted that evidence from clinical trials supports the efficacy of physical exercise as a treatment for depression over a 2–4 month period.[37]
Yoga is appropriate for individuals of all ages and fitness levels. Those who are seeking a workout that increases their mind, body and spiritual awareness will find yoga to be a good fit for them. Those who wish to increase their fitness level at a slower pace may find that yoga is perfect for them, although the physical intensity is just as high as in many other exercise methods. Yoga exercises utilize a variety of muscle groups at the same time, so an entire body workout is often achieved during each class. Yoga is effective in toning muscles without creating a bulky look.
If you really want to get in shape, why not turn some everyday tasks into exercise opportunities? We know you're lazy, so between your DVD-guided workout sessions, finding ways to incorporate exercise into daily tasks may help to make exercise less of an intimidating, dark, scary monster that looms ahead. Finding room for exercise in your daily life could even make exercise—dare I say it—fun.
Super Set. Instead of tweeting about how sweaty you are after each set, push muscle groups by coupling exercise with another set that focuses on a different body part, for example: back and chest, bi's and tri's, Tom and Jerry. Research suggests lifting in supersets can be just as effective as normal sets at building strength while adding an additional cardio component The metabolic costs of reciprocal supersets vs. traditional resistance exercise in young recreationally active adults. Kelleher, A.R. Musculoskeletal and Human Performance Laboratories, Department of Exercise Science, Syracuse University, Syracuse, New York, USA; Journal of Strength and Conditioning Research. 2010 Apr;24(4):1043-51.. Or for added punch, do similar body parts — shoulders and shoulders, legs and legs — for a serious burn.
Tip: Be sure you know which methods of exercise your company allows, and understand the tax consequences discussed in the third, fourth, and fifth articles in this series. Check the stock plan documents for each stock option grant, and complete necessary paperwork before the date you intend to exercise. Ask the stock plan administrator (or appropriate person) for exercise procedures pertaining to each method. Not all companies may have written procedures.

The goal in training competitive athletes is to provide training loads that are effective in improving performance. At some stages during the training process, athletes may experience an unexplainable decrease in performance. This might happen when prolonged excessive training takes place concurrent with other stressors and insufficient recovery. This unexplainable performance decrements can result in chronic maladaptations that can lead to the overtraining syndrome (OTS). A keyword in the recognition of OTS might be “prolonged maladaptation” not only of the athletic performance but also of several biological, neurochemical and hormonal regulation mechanisms. When athletes deliberately use a short-term period (eg, training camp) to increase training load, they can experience short-term performance decrement, without severe psychological or lasting other negative symptoms.1 2 This functional over reaching (FO) will eventually lead to an improvement in performance after recovery. However, when athletes do not sufficiently respect the balance between training and recovery, non-functional over-reaching (NFO) can occur.1 2 At this stage, the first signs and symptoms of prolonged maladaptation such as performance decrements, psychological disturbance (decreased vigour, increased fatigue) and hormonal disturbances are present, and the athlete will need weeks or months to recover. The distinction between NFO and OTS is very difficult and will depend on the clinical outcome and exclusion diagnosis.


After options vest, you may purchase the company stock at the option price any time before the options expire. But exercises, as well as sales, may be prohibited during any "blackout" periods, or allowed only during window periods. Company policies must be carefully followed, as well as federal and state securities laws. Optionholders are responsible for keeping up with current insider trading regulations.

Tabata training is a form of high-intensity interval training. It consists specifically of eight rounds of high-intensity exercise using a 20 seconds on (at full capacity) and 10 seconds off (rest) format. The goal is to push yourself as hard as you can during the 20 second on period. Tabata only requires one exercise, but you can combine different strength and aerobic exercises to make your own Tabata routine. Here’s a simple example of Tabata for one exercise:
The benefits of exercise have been known since antiquity. Dating back to 65 BCE, it was Marcus Cicero, Roman politician and lawyer, who stated: "It is exercise alone that supports the spirits, and keeps the mind in vigor."[143] Exercise was also seen to be valued later in history during the Early Middle Ages as a means of survival by the Germanic peoples of Northern Europe.[144]
In 1918 following WWI, Pilates returned to Germany where he started training dancers and quickly gained acclaim. However, to avoid Contrology being used by the German army, Pilates moved to the USA in 1925 and opened the Pilates Universal Studio in Manhattan.39,42 Balanced Body, Inc. [Internet]. Origins of Pilates. 2015 Aug 30 [cited 2015 Aug 30]. Available from: https://www.pilates.com/BBAPP/V/pilates/origins-of-pilates.html.
It takes the gastrointestinal tract about 3 to 4 hours to completely digest a full meal. Note too that the digestion phase varies between what you are eating -- for example if you ate a banana, you can exercise after 30 minutes or 1 hour after eating it but if you ate a steak, it would take you about 3 hours before it would be good to begin exercise. That said, most people find that eating trail mix mid-hike doesn't prevent them from continuing to walk, as human beings were built to eat and move.

Video Abstract for the ESSR 45.1 article “Mechanisms and Mediators of the Skeletal Muscle Repeated Bout Effect” from author Rob Hyldahl. Skeletal muscle adapts to exercise-induced damage by orchestrating several but still poorly understood mechanisms that endow protection from subsequent damage. Known widely as the repeated bout effect, we propose that neural adaptations, alterations to muscle mechanical properties, structural remodeling of the extracellular matrix, and biochemical signaling work in concert to coordinate the protective adaptation.
Children who participate in physical exercise experience greater loss of body fat and increased cardiovascular fitness.[23] Studies have shown that academic stress in youth increases the risk of cardiovascular disease in later years; however, these risks can be greatly decreased with regular physical exercise.[24] There is a dose-response relation between the amount of exercise performed from approximately 700–2000 kcal of energy expenditure per week and all-cause mortality and cardiovascular disease mortality in middle-aged and elderly populations. The greatest potential for reduced mortality is in the sedentary who become moderately active. Studies have shown that since heart disease is the leading cause of death in women, regular exercise in aging women leads to healthier cardiovascular profiles. Most beneficial effects of physical activity on cardiovascular disease mortality can be attained through moderate-intensity activity (40–60% of maximal oxygen uptake, depending on age). Persons who modify their behavior after myocardial infarction to include regular exercise have improved rates of survival. Persons who remain sedentary have the highest risk for all-cause and cardiovascular disease mortality.[25] According to the American Heart Association, exercise reduces the risk of cardiovascular diseases, including heart attack and stroke.[22]
Findings indicated that exercise is beneficial for reducing pain and improving function in individuals with RCIS. The effects of exercise might be augmented with implementation of manual therapy. In addition, supervised exercise might not be more effective than a home exercise program. Many articles had methodologic concerns and provided limited descriptions of specific exercises, which made comparing types of exercise among studies difficult. Based on the results, Kuhn generated a physical therapy protocol using evidence-based exercise that could be used by clinicians treating individuals with impingement syndrome. This evidence-based protocol can serve as the criterion standard to reduce variables in future cohort and comparative studies to help find better treatments for patients with this disorder.
You’ve been cleared to exercise but now what? Don’t worry, we’ve got you covered. Our expert guidance will provide you with the foundational strength needed to get you feeling like yourself again while adding an angle of rehabilitative care to re-connect, heal, & re-strengthen your postpartum body. We will safely progress you through exercises that are meant to challenge your body and stimulate your mind while gearing you up to be the strong mom you’re aiming to be. We guarantee that with our training, your fitness regimen will be more effective than ever before.
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Whenever I’m feeling overwhelmed and super busy, the first thing that always falls off my schedule is hitting the gym—even though I know making the extra time to sweat it out will make me feel better and more centered. But I’ve realized that you can always find a way to prioritize the things that matter, even if you have to get creative with the way you fit them in.

"Exercise is the magic pill," says Michael R. Bracko, EdD, FACSM, chairman of the American College of Sports Medicine's Consumer Information Committee. "Exercise can literally cure diseases like some forms of heart disease. Exercise has been implicated in helping people prevent or recover from some forms of cancer. Exercise helps people with arthritis. Exercise helps people prevent and reverse depression."
This move is sure to get your heart racing in no time. Master a basic lunge before progressing to this version. With right foot ahead of left foot and core tight, drop into a low lunge, bending both knees to 90 degrees. Now jump up, switching feet in middair so you land with left foot ahead of right foot and immediately drop into a low lunge on the other side.
PiYo isn't like standard Pilates and yoga classes that make you hold long, intense poses, or lead you through dozens of repetitive, microscopic core movements. PiYo speeds everything up—including your results—by introducing you to dynamic, flowing sequences that can burn serious calories at the same time as they lengthen and tone your muscles and increase your flexibility.
When stress is chronically induced, as in NFO and OTS, two specific mechanisms could occur: first, when corticosteroid levels are chronically too high, a hypersensitivity of the receptors will occur, this can lead to a disinhibition of CRHproducing neurons, which in turn will lead to an intensified release of ACTH (as seen in the second exercise bout in the NFO athletes). When the chronic stress situation continues and glucocorticoid receptors are chronically activated (which occurs in post-traumatic stress disorder17 and depression),25 a blunted ACTH response to CRH will occur.28
Torque signal and knee angle signal were recorded using the same dynamometer as for the OLDE (Cybex NORM isokinetic dynamometer, CMSi, Computer Sports Medicine Inc., Stoughton, USA). During the tests a two shoulder harnesses and a belt across the abdomen limited extraneous movement of the upper body. Torque signal and knee angle signal were digitized on-line at a sampling frequency of 1 kHz using a computer, and stored for analysis with commercially available software. Torque signal was filtered prior to data analysis (Butterworth low-pass filter at 100 Hz). Torque signal, knee angle signal and EMG signal were recorded with the same device (MP150, Biopac Systems Inc., Goleta, USA) and analyzed with the same commercially available software (Acqknowledge 4.2 for MP Systems, Biopac Systems Inc., Goleta, USA).
Jump up ^ Zhou Y, Zhao M, Zhou C, Li R (July 2015). "Sex differences in drug addiction and response to exercise intervention: From human to animal studies". Front. Neuroendocrinol. 40: 24–41. doi:10.1016/j.yfrne.2015.07.001. PMC 4712120. PMID 26182835. Collectively, these findings demonstrate that exercise may serve as a substitute or competition for drug abuse by changing ΔFosB or cFos immunoreactivity in the reward system to protect against later or previous drug use. ... As briefly reviewed above, a large number of human and rodent studies clearly show that there are sex differences in drug addiction and exercise. The sex differences are also found in the effectiveness of exercise on drug addiction prevention and treatment, as well as underlying neurobiological mechanisms. The postulate that exercise serves as an ideal intervention for drug addiction has been widely recognized and used in human and animal rehabilitation. ... In particular, more studies on the neurobiological mechanism of exercise and its roles in preventing and treating drug addiction are needed.
The mental benefits of Pilates include an increase in the ability to focus. It takes a great deal of concentration to coordinate your breath and body position during workouts. In fact, Joseph Pilates often referred to his method as “the thinking man’s exercise” due to the improvement in memory and other cognitive functions that results from doing it. A clear mind also reduces stress levels, which translates to an improvement in your overall health.
Video Abstract for the ESSR 46.2 article “Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle With Aging” from author Donato Rivas. Age-induced loss of skeletal muscle mass and function, termed sarcopenia, may be the result of diminished response to anabolic stimulation. This review will explore the hypothesis that alterations in the expression of microRNA with aging contributes to reduced muscle plasticity resulting in impaired skeletal muscle adaptations to exercise-induced anabolic stimulation.
Wall sit while you brush your teeth. You should be brushing your teeth for two minutes at least twice a day, so take advantage of that precious time by doing some wall sits. At first, you'll probably only last for around 20 seconds, but make it a goal to work up to wall sitting for the whole two minutes that you're brushing your teeth. You might surprise yourself!
When shopping, take some extra laps around the store. Instead of making your shopping trip efficient, take your time and stroll around the store a couple times. If that feels too aimless, add an objective of memorizing the store's layout. Or, when grocery shopping, don't group items on your list by type. Instead, randomize the order so that you get one thing from the produce section and then get something from a different section before getting your next produce item.
The baseline characteristics of the study participants are presented in Table 1. No differences between the training groups existed at study entry. In both groups, men spent more hours in sedentary behavior and had significantly higher weight, height, and VO2peak compared to women. Contrary, more women than men performed at least 30 min of daily physical activity (Table 1). The included participants had higher VO2peak (11%) compared to those with no exercise logs. They also had higher VO2peak (17%) and height (1.7%) compared to dropouts, but a lower BMI (3.7%) (p < 0.05). A higher proportion of the included participants performed 30 min of daily physical activity compared to the dropouts (77.3% vs. 66.1%, p < 0.05).
Tip: Be sure you know which methods of exercise your company allows, and understand the tax consequences discussed in the third, fourth, and fifth articles in this series. Check the stock plan documents for each stock option grant, and complete necessary paperwork before the date you intend to exercise. Ask the stock plan administrator (or appropriate person) for exercise procedures pertaining to each method. Not all companies may have written procedures.
In 1937, Randell’s number-two Thomas was sent to Australia to lecture on the St Thomas Project, teach the exercises, and assist local physiotherapists with the program’s implementation.35 Evans EP. The history of the New South Wales branch of the Australian Physiotherapy Association. Aust J Physiother. 1955;1(2):76–8.10.1016/S0004-9514(14)60817-5[Crossref] [Google Scholar] There are multiple indications of an unknown video Thomas made during this visit, and it was reported later that as a result of the visit, the St Thomas method was implemented in maternity hospitals in Sydney and Melbourne; the exercises were used by physiotherapists on an individual basis and that Thomas was remembered as a pioneer of Australian antenatal physiotherapy.29,35,36 Sydney Morning Herald [Internet]. Thomas BM: Obituary (1940). 2014 Oct 23 [cited 2015 Aug 30]. Available from: http://www.tiveyfamilytree.com/Barbara-Mortimer-Thomas-Death-Article-SMH-11-9-1940.htm.

In the present study, we measured muscle endurance by completion of time to exhaustion tests where the subject has to maintain a fix workload for as long as possible. All time to exhaustion tests lasted less than ten minutes, confirming that OLDE was performed at high intensity. The duration of the time to exhaustion tests in the present study is in accordance with previous studies using the same exercise on a different ergometer [11, 17, 18]. Relative reliability refers to the degree to which individuals maintain their position in a sample with repeated measurements [30]. The ICC value of 0.795 can be interpreted as a questionable reliability (ICC < 0.8), close to the threshold for good reliability (0.8 < ICC < 0.9) [19]. However, as no consensus really exists on threshold to interpret ICC results [31], the practical significance of its value has to be determined with caution by the readers according to their future use of the present protocol. Absolute reliability refers to the degree to which repeated measurements vary for individuals [30]. Traditionally, time to exhaustion tests are known to present a greater CV (CV > 10%) than time trials (i.e. subjects has to perform the greater amount of work possible in a fixed time/distance; CV < 5%) [20]. Interestingly, in our study the CV is below 10%, confirming the great reliability of our novel high intensity OLDE protocol to measure muscle endurance, this despite the small sample size, chosen to be in accordance with previously published studies using the same protocol [8, 11, 17]. This great reliability is confirmed by the typical error of measurement value of 0.30 min, corresponding to 5% of the averaged performance value. Finally, as the typical error of measurement value was slightly above the smallest worthwhile change calculated (0.28 min), it is unlikely that our novel high intensity OLDE protocol can be used to detect small differences in performance.


Anaerobic exercise, which includes strength and resistance training, can firm, strengthen, and tone muscles, as well as improve bone strength, balance, and coordination.[3] Examples of strength moves are push-ups, pull-ups, lunges, and bicep curls using dumbbells.[3] Anaerobic exercise also include weight training, functional training, eccentric training, interval training, sprinting, and high-intensity interval training increase short-term muscle strength.[3][5]
The hypothalamus is under the control of several “higher” brain centres and several neurotransmitters 13 known to play a major role in various neuroendocrine and behavioural functions, for example, activation of the HPA axis, feeding and locomotion.14 Therefore, the typical HPA axisrelated hormones cortisol, adrenocorticotrophic hormone (ACTH), prolactin (PRL) and human growth hormone (GH) were targeted in the present study.
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