The symptoms associated with OTS, such as changes in emotional behaviour, prolonged feelings of fatigue, sleep disturbances and hormonal dysfunctions are indicative of changes in the regulation and coordinative function of the hypothalamus.8 19 Previous studies have shown different results for stress-induced hormonal responses.6 20 21 Results from a previous study10 and the present study show that contradictory findings cannot solely be explained by different measurement methods and/or definitions used. From figs 3 and 4, it is clear that hormonal responses to one single exercise bout are not sensitive enough to distinguish NFO from OTS.
^ Jump up to: a b McKee AC, Daneshvar DH, Alvarez VE, Stein TD (January 2014). "The neuropathology of sport". Acta Neuropathol. 127 (1): 29–51. doi:10.1007/s00401-013-1230-6. PMC 4255282. PMID 24366527. The benefits of regular exercise, physical fitness and sports participation on cardiovascular and brain health are undeniable ... Exercise also enhances psychological health, reduces age-related loss of brain volume, improves cognition, reduces the risk of developing dementia, and impedes neurodegeneration.
"Exercise is the magic pill," says Michael R. Bracko, EdD, FACSM, chairman of the American College of Sports Medicine's Consumer Information Committee. "Exercise can literally cure diseases like some forms of heart disease. Exercise has been implicated in helping people prevent or recover from some forms of cancer. Exercise helps people with arthritis. Exercise helps people prevent and reverse depression."

Continuous aerobic exercise can induce a transient state of euphoria, colloquially known as a "runner's high" in distance running or a "rower's high" in crew, through the increased biosynthesis of at least three euphoriant neurochemicals: anandamide (an endocannabinoid),[73] β-endorphin (an endogenous opioid),[74] and phenethylamine (a trace amine and amphetamine analog).[75][76][77]
(2) Active Phase (between 60% and 84% HRR). Continuous dynamic and interval training mode exercise involving large muscle activities with an increasing level of difficulty and intensity. Subjects began with a short walk, alternated with various step exercises (e.g., both side and forward-backward step up and down on the platform, with alternate footsteps). Then, they went on performing alternate upper-limb lifts (while keeping inferior limbs flexed) and lower limb flexions and extensions (knee lifts, both side and forward-backward leg lifts, and leg curls), as a sort of brief and easy sequence to be repeated for a fixed time. Integrated multiple plane exercises for upper and lower limbs using elastic resistances (Xertube®) completed the last part of the Active Phase. To reach the goal of gradually augmenting the intensity of the program, the coach continuously checked the HRR level of subjects who were progressively increasing the duration and the number of exercises. The resistance of the elastic bands was also increased by one level (from very light to medium) every 4 weeks.
Evidence from HIIT studies conducted under controlled laboratory conditions has provided proof-of-concept of efficacy [9]. However, it has been argued that HIIT has high efficacy but low effectiveness [16], and long-term exercise interventions carried out under free-living conditions have been asked for to investigate whether HIIT is feasible as a public health initiative among older adults [9, 16]. Our data showed that both training groups reported on average more than two exercise sessions per week throughout the year. Approximately 60% of the sessions in the HIIT group were performed with a self-reported high-intensity (≥15 Borg scale), indicating that older adults are able to perform HIIT over a long time-period without strict supervision. However, women had a lower proportion of sessions with high-intensity exercise compared to men. This result is in line with previous findings that women (aged 60–67 years) are less likely than men to prefer vigorous physical activity [23].
Yoga is appropriate for individuals of all ages and fitness levels. Those who are seeking a workout that increases their mind, body and spiritual awareness will find yoga to be a good fit for them. Those who wish to increase their fitness level at a slower pace may find that yoga is perfect for them, although the physical intensity is just as high as in many other exercise methods. Yoga exercises utilize a variety of muscle groups at the same time, so an entire body workout is often achieved during each class. Yoga is effective in toning muscles without creating a bulky look.
Jump up ^ Farina N, Rusted J, Tabet N (January 2014). "The effect of exercise interventions on cognitive outcome in Alzheimer's disease: a systematic review". Int Psychogeriatr. 26 (1): 9–18. doi:10.1017/S1041610213001385. PMID 23962667. Six RCTs were identified that exclusively considered the effect of exercise in AD patients. Exercise generally had a positive effect on rate of cognitive decline in AD. A meta-analysis found that exercise interventions have a positive effect on global cognitive function, 0.75 (95% CI = 0.32–1.17). ... The most prevalent subtype of dementia is Alzheimer’s disease (AD), accounting for up to 65.0% of all dementia cases ... Cognitive decline in AD is attributable at least in part to the buildup of amyloid and tau proteins, which promote neuronal dysfunction and death (Hardy and Selkoe, 2002; Karran et al., 2011). Evidence in transgenic mouse models of AD, in which the mice have artificially elevated amyloid load, suggests that exercise programs are able to improve cognitive function (Adlard et al., 2005; Nichol et al., 2007). Adlard and colleagues also determined that the improvement in cognitive performance occurred in conjunction with a reduced amyloid load. Research that includes direct indices of change in such biomarkers will help to determine the mechanisms by which exercise may act on cognition in AD.
(3) Recovery Phase (<60% HRR). Postural control and spine mobility exercises in a quadrupedal position with the platform support, exercises of static balance over either 4 or 2 supports, eyes either open or closed, and with core muscle activation. The latter phase also included various poststretch exercises to restore the preexercise muscle length.
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