Video Abstract for the ESSR 46.2 article “Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle With Aging” from author Donato Rivas. Age-induced loss of skeletal muscle mass and function, termed sarcopenia, may be the result of diminished response to anabolic stimulation. This review will explore the hypothesis that alterations in the expression of microRNA with aging contributes to reduced muscle plasticity resulting in impaired skeletal muscle adaptations to exercise-induced anabolic stimulation.
This is what you should be doing before exercise to raise your heart rate and body temperature in preparation for the workout. During this type of warm-up, you moving through stretches and light exercises without stopping (as opposed to a passive stretches, which are held in place, like you do in a cool-down). This helps increase mobility and range of motion so you can get deeper into exercises. Here are five great dynamic warm-up stretches to try.
Tabata Intervals. The great thing about many of these techinques is the time saving aspect, and Tabata Intervals are definitely time savers. Developed by Dr. Izumi Tabata for Olympic athletes, Tabata Protocol is a form of High Intensity Interval Training (HIIT) where 20 seconds of work is coupled with 10 seconds of rest then repeated for 8 total rounds Metabolic profile of high intensity intermittent exercises. Tabata, I., Irisawa, K., Kouzaki, M., et al. Department of Physiology and Biomechanics, National Institute of Fitness and Sports, Kanoya City, Japan. Medicine & Science in Sports & Exercise 1997 Mar;29(3):390-5.. The 20 seconds work/10 seconds rest pattern has been shown to tax both aerobic and anaerobic pathways more — and in less time — than intense exercise with longer rest periods, meaning improved overall cardiovascular fitness. This protocol can be done with running/rowing/swimming, bodyweight exercises, or weighted movements.

The first step to any workout routine is to evaluate how fit you are for your chosen physical activity. Whenever you begin an exercise program, it's wise to consult a doctor. Anyone with major health risks, males aged 45 and older, and women aged 55 and older should get medical clearance, says Cedric Bryant, PhD, chief exercise physiologist for the American Council on Exercise.

However, our goal is not necessarily to move more weight but to safely and efficiently target your muscles. By dramatically slowing the speed of the movements and ensuring that the weight smoothly changes directions, we virtually eliminate the possibility of injury. Excessive momentum is removed so only the muscles (and not the joints, tendons, or ligaments) are taxed.
The exercise videos became a series, and Fonda eventually released 23 workout videos. Fonda's exercise videos were such a success because they were the first media of their time to send the message that it was socially acceptable for women to participate in exercise culture and become muscular. Fonda's videos also helped to spark the aerobic exercise trend of the 1980s, not to mention the period's iconic fashion trend: a neon exercise outfit with a leotard and leg warmers. The aerobic exercise craze became so widespread that a Muppets parody tape titled Miss Piggy's Aerobique Exercise Workout Album was released in 1982. The album cover featured Miss Piggy in a Fonda-esque exercise outfit, complete with leg warmers and a leotard, in a pose imitating that which was famously modeled by Jane Fonda on the cover of her first tape.

I must confess: the title of this section is misleading, because while most of us associate the first home workouts with fitness icons Jane Fonda and Richard Simmons, they were not the first ones to bring workouts inside our homes. In fact, before there were VHS tapes, before there were even televised workouts, there were the audio-only vinyl record workouts, nicknamed vinylcise.


The beneficial effect of exercise on the cardiovascular system is well documented. There is a direct correlation between physical inactivity and cardiovascular mortality, and physical inactivity is an independent risk factor for the development of coronary artery disease. Low levels of physical exercise increase the risk of cardiovascular diseases mortality.[22]
Physical exercise is important for maintaining physical fitness and can contribute to maintaining a healthy weight, regulating digestive health, building and maintaining healthy bone density, muscle strength, and joint mobility, promoting physiological well-being, reducing surgical risks, and strengthening the immune system. Some studies indicate that exercise may increase life expectancy and the overall quality of life.[10] People who participate in moderate to high levels of physical exercise have a lower mortality rate compared to individuals who by comparison are not physically active.[11] Moderate levels of exercise have been correlated with preventing aging by reducing inflammatory potential.[12] The majority of the benefits from exercise are achieved with around 3500 metabolic equivalent (MET) minutes per week.[13] For example, climbing stairs 10 minutes, vacuuming 15 minutes, gardening 20 minutes, running 20 minutes, and walking or bicycling for transportation 25 minutes on a daily basis would together achieve about 3000 MET minutes a week.[13] A lack of physical activity causes approximately 6% of the burden of disease from coronary heart disease, 7% of type 2 diabetes, 10% of breast cancer and 10% of colon cancer worldwide.[14] Overall, physical inactivity causes 9% of premature mortality worldwide.[14]

Leg muscle pain, defined as “the intensity of hurt that a subject feel in his quadriceps muscles only” [26], was measured during the incremental test (at the end of each minute) and during the time to exhaustion tests (at the end of the warm-up and every 30 s) using the Cook scale [26]. Standardized instructions for the scale were given to each subject before the warm-up. Briefly, subjects were asked to rate the feelings of pain specifically in their quadriceps and not to report other pains they may have experienced (e.g., seat discomfort). Subjects were also asked to not use this rating as an expression of perceived effort [24].
The practice of the MMB methods is generally emphasized in three areas. Firstly, human movement is achieved with involvement of a centrally controlled dynamic synergy between the body’s stability and mobility movement elements.61 Hoffman J, Gabel P. Expanding Panjabi’s stability model to express movement: A theoretical model. Med Hypotheses. 2013;80(6):692–7.10.1016/j.mehy.2013.02.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar] This ensures all the muscles of the body concurrently employ or counter movement forces which results in visible harmonious movements. Secondly, functionality is required as the MMB is aimed at correct natural movements that reflect the requirements of activity and life in the modern world. Consequently, non-functional movements are unjustified as an MMB exercise. Thirdly, learning of MMB exercises requires a cognitive focus on achieving harmonious functional movements. With practice, the cognitive learning process enables an automatic and harmonious physical performance, making the exercises as well as everyday tasks easier, safer, and more efficient. The MMB exercises were intended by their creators to be healthy and enjoyable, a cultural alternative to the practice of aggressively overtraining the body and accepting pain and injury as normal components of sport.
It’s no secret that Beyoncé is a crazy-good performer, and while we could never mimic her vocals, with some coaching, we thought we could pick up her dance moves. That’s why we were so excited to discover this video series featuring choreographer Frank Gatson, Jr., who breaks down every portion of Beyoncé’s Let’s Move! campaign, which features a remix of “Get Me Bodied.” Watch the first instructional portion and then the second one to learn the entire routine.
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The overhead squat requires strength and flexibility. HOW TO DO IT: You can take the bar from a squat rack by snatching it overhead or by cleaning and jerking it. The arms should be wider on the bar, very similar to a snatch grip. The feet should be a little outside of shoulder-width. Brace your core, and send your butt back into a squat position while keeping your arms locked overhead. A good cue to think of is “show me your pits” or bending the bar, which automatically externally rotates the shoulders and locks them into a strong position. Once you have reached below parallel, drive your knees out, squeeze your glutes and stand the bar back up. MUSCLES USED: Glutes, quads, hamstrings, calves, core, shoulders and back.

The severity of angina and the effects of therapeutic interventions in patients with coronary artery disease have been assessed by determining changes in both exercise performance and the triple product (TP) of heart rate, systolic pressure, and ejection time occurring at angina. However, the validity of conclusions based on such changes is uncertain since the effects of different exercise protocols on these variables have not been determined. Twelve patients with angina were studied during upright bicycle exercise; repeated bouts of exercise using a standard protocol of 20-w increments every three minutes produced no consistent changes in TP at angina. When exercise began 20 to 60 w above the work load of the standard protocol that produced angina, exercise capacity was reduced (average 1'40'' vs. 4'40'', P < 0.001), and triple product at angina exceeded control anginal values (average 4,840 vs. 4,150, P < 0.001). In the control studies nitroglycerin (TNG) and carotid sinus nerve stimulation (CSNS) enabled patients to exercise to a higher level, although the triple product at angina was unaltered. However, at the higher work load TNG and CSNS exerted only minimal effects on exercise capacity, indicating that if the work load is excessive, a reduction in myocardial oxygen consumption produced by a therapeutic intervention may be comparatively minor so that a potentially salutary effect would be masked. We conclude that work loads causing angina in less than three minutes cannot reliably be used for studying the effects of therapy. However, if progressive work loads are chosen which cause angina in the control studies in three to six minutes, exercise capacity and triple product at angina provide important information about the efficacy and mechanism of action of a therapeutic intervention.
The novelty of the present study is that of demonstrating the possibility of applying a specific vigorous physical exercise program [17] on healthy elderly adults over 65 years and evaluating its effects on functional capacity using the classical SFT [3]. To administer the high exercise intensity, we used a HR control under continuous accurate visual monitoring by a sport scientist. As expected, after only 12 weeks of training, we found significant enhancements of almost all skills tested. Our results clearly show that our VE program is relevant and has a positive impact on people over 65 in helping them to maintain a high quality of life. The difference from most of the literature [18–22] regards the exercise protocol intensity, which is usually milder than ours. Also, in the aforementioned studies there was a poor attention about the consequences of the exercise program on general quality of life of subjects. They mainly focused on the attenuated risks of falling. On the contrary, the SFTs applied in our study clearly show that our VE program may ameliorate several motor abilities and in turn the general quality of life in healthy elderly adults over 65 years of age. However, two other studies showed that elderly people need to exercise close to their limit of maximum capacity [23, 24] to improve their physical fitness but, unlike the present research, they were conducted on patients who were in deconditioning status linked to their chronic illnesses.
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