KE EMG RMS corresponds to the sum of EMG RMS of the following muscles: Vastus Lateralis, Rectus Femoris and Vastus Medialis. Isokinetic KE MVCs were performed at 60 (panel, A), 100 (panel B) and 140 (panel C) deg/s. Isokinetic KE MVCs were measured pre-exercise (pre, average of all three sessions pre-exercise values), shortly after exhaustion (13 ± 4 s after exhaustion), 20 s following exhaustion test (P20) and 40 s following exhaustion test (P40). Data are presented as mean (SE).
Ready to begin rehabbing your core before you’re cleared to exercise? We can help with this too! Have a talk with your care provider and we’ll take care of the rest. During this early rehabilitation stage, we keep it simple, helping you integrate our techniques into your new life, progressing you when you and your body are ready for the next steps. The way we connect to our body in the first several weeks postpartum can really set the stage for the months ahead.
Trainer Natalie Uhling is all about the tried and true burpee for full body conditioning in 30 seconds—though she recommends three sets of 30-second burpees with a 15-second break between sets. For “quality” burpees, she says to do the following: Start with your feet shoulder-width apart and a slight bend in your knees; make sure that you are not pushing through the toes of your feet but you are starting centered. As you jump, remember to land softly because you want to protect your joints. When you make your way down to the plank position, make sure your core is protected, that means keep your hips square and your butt out of the sky.

Spark People shares short videos for all different types of workouts. There are several categories -- Abs, Cardio, Yoga and Pilates, as well as others that diver into healthy cooking and eating ideas. These workouts are great when you are pinched for time. Choose a 10-12 minute routine and squeeze in some activity where you normally would have skipped it altogether.
The main strength of this study is the large data material on exercise patterns. Most research on exercise pattern has used a cross-sectional design whereas we followed older adults over a one-year period and collected data from each exercise session they performed. Furthermore, this is the first study to assess differences in exercise patterns between older adults instructed to follow MCT versus HIIT.
It features 12 different 30-second exercises, with five seconds of rest in between. It’s great for beginners and athletes, syncs with your iPhone Health App to take your other daily movement into account, and the workout library has 22 presets that you can customize to create thousands of variations. You can swipe right or left during the exercises to see how much time you have left, watch the instructor, or listen to music from your iTunes.
You probably already spend one to three minutes brushing and flossing your teeth at least once a day. Why not brush your teeth while holding a deep squat, or while doing side leg lifts? These things are perfectly doable and add no additional time to your tooth-brushing activities. Simply tell yourself that you have no excuse for brushing your teeth without holding a deep squat. No matter how tired you are.
Making older adults exercise and keeping them in exercise programs is a major challenge. Understanding how older adults prefer to exercise may help developing tailored exercise programs and increase sustained exercise participation in ageing populations. We aimed to describe exercise patterns, including frequency, intensity, type, location and social setting of exercise, in older adults instructed to follow continuous moderate-intensity training (MCT) or high-intensity interval training (HIIT) over a one-year period.
Insanity: The Asylum is the "sequel" to Insanity, and it pushes you hard, further, deeper in ways that the original Insanity workout wasn't meant to do. I'm going to discuss what to expect in this DVD series, then tell you a little about my results. To give you some perspective, I'm almost 40, and only 2.5 months ago, weighed more than I ever had before (222 pounds). I'm pretty short, so I looked like a man-dumpling. I did insanity (all 63 days, never missed a workout), lost 22 pounds, and then was looking for the next thing to help me keep losing. Fortune struck, and this set came out at just the right time. I segued directly into this series. Here's the story.
When visual inspection gave an indication for group differences, parametric statistical analyses were performed through ANOVA with repeated measures with one withinsubjects factor (post-values for first and second exercise test) and one between-subjects factor (NFO or OTS) or through an independent samples t test. Those analyses were performed in SPSS V.15.0. Sensitivity was also calculated for these variables by dividing the number of correct OTS or NFO diagnoses by hormonal analysis by the total number of OTS or NFO diagnoses according to the consensus statement.1 Sensitivity was presented as a ratio. The denominator varies because of random missing values.
Seven minutes of exercise per day a few times a week though isn’t a magical elixir that will give you a bikini-ready body in a few weeks. Michelle Golla, of Denver-based Boost 180 Fitness, says, “it's important not to set unrealistic expectations for a 7-minute workout. It will not completely transform your body, but it is a great way to get your heart pumping and burn calories all day long when you're pressed for time.”  

To start toning your abs by hitting up the lower abdominal muscles, Riggins suggests 30 seconds of leg raises. Here’s how: Turn on your back with legs straight and your feet and ankles together. Raise your legs up and down in a vertical position from your body, while keeping your belly button. Slowly bring legs back down, but if that is too difficult, tuck your knees. (And be careful not to strain your lower back!)
By 1925, Margaret Morris had already integrated remedial exercises within her newly established dance school, Margaret Morris Movement (MMM). Her philosophy claimed that natural dance moves should be healthy and constructive for the body and mind, rather than the deleterious moves dancers were expected to practice and perform at the time. Morris saw the connections between breathing, stamina, range of motion, posture, health, vitality, and how these freed the body to dance and the mind to be creative.49 Morris M. My life in movement. London: Peter Owen Publishers; 1969. [Google Scholar] This philosophy extended itself to the use of natural dance moves as remedial exercises and a healthy active lifestyle. During 1925 and 1926, Morris presented her method to doctors and midwifes in England, France, and Switzerland, among them the St Thomas team. As a result of this meeting, Morris enrolled to study physiotherapy under Randell and graduated in 1933 with distinction.30 Margaret Morris Movement (MMM) [Internet]. Margaret Morris - Biography. 2015 Aug 30 [cited 2015 Aug 30]. Available from: http://www.margaretmorrismovement.com/MargaretMorris. [Google Scholar] Throughout her decade of collaboration with Randell and the St Thomas Project, Morris continued to educate and run MMM with great appreciation from top-tier dancers, students, and artistic critiques. By 1939, her teachers developed movement education and dance centers in 10 countries, most still active today (Figures 7–9).30 Margaret Morris Movement (MMM) [Internet]. Margaret Morris - Biography. 2015 Aug 30 [cited 2015 Aug 30]. Available from: http://www.margaretmorrismovement.com/MargaretMorris. [Google Scholar]
Exercising looks different in every country, as do the motivations behind exercising.[2] In some countries, people exercise primarily indoors, and in others, people primarily exercise outdoors. People may exercise for personal enjoyment, health and well-being, social interactions, competition or training, etc. These differences could potentially be attributed to geographic location, social tendencies, or otherwise.
Video Abstract for the ESSR 45.4 article “Mechanisms Associated With Physical ActivityBehavior: Insights From Rodent Experiments” from authors Michael D. Roberts, Gregory N. Ruegsegger, Jacob D. Brown, and Frank W. Booth. Dopaminergic signaling differences in the nucleus accumbens (NAcc) seemingly predispose rats to adopt different physical activity behaviors. Physical activity behavior also may be regulated through peripheral mechanisms (i.e., muscle and fat derived as well as hormonal signals). We hypothesize that physical activity behavior is regulated by the convergence of central and peripheral mechanisms onto the NAcc.
Walking was the most common exercise type in both training groups (Fig. 3). Compared to HIIT, MCT had a significantly higher proportion of sessions with walking and resistance training. Contrary, compared to MCT, HIIT had a higher proportion of sessions with cycling, combined endurance and resistance training, other types of endurance training (e.g. aerobic, treadmill), jogging, swimming and dancing. There were no group differences regarding cross-country skiing and domestic activities (e.g. housework, gardening) (Fig. 3).
The bent-over row is performed while leaning over, holding a weight hanging down in one hand or both hands, by pulling it up towards the abdomen. This is a compound exercise that also involves the biceps, forearms, traps, and the rear deltoids. The torso is unsupported in some variants of this exercise, in which case lifting belts are often used to help support the lower back.

Former ballet dancer and Ballet Beautiful founder Mary Helen Bowers has serious fitness cred thanks to training Natalie Portman for her role in Black Swan. With this free workout video, she takes her expertise outside the dance studio. The 15-minute mat workout will help tone your lower body with graceful ballet-inspired movements like bridge variations.

The exercises developed by Checkley, Müller, Randell, Alexander, Pilates, and Morris were secular in nature. The holistic unity between harmonious movements and beauty, health, performance and youth, between the body and mind, and between human and nature were all emphasized yet these universal concepts were unimpeded by religious, political, or commercial influences. The exercises were simply harmonious functional human movements learned from observations of nature.
The deadlift is one of the foundational strength movements in any exercise program. HOW TO DO IT: The deadlift begins with the bar on the ground. You can perform this with a regular grip or an alternating grip, which means one hand facing towards your body and one hand facing away. With a proud chest and locked core, pull the bar up while keeping it as close to your body as possible. Use your hip hinge and push your knees back to keep your body over the bar. Then extend the hips and squeeze the glutes to complete the move. MUSCLES USED: Glutes, quads, hamstrings, calves, back and core.
Back in mid-century America, you did old-style sit-ups, which were once regarded as the gold standard of iron-gut, military discipline. Maybe they still are, so if your idea of "manly" is messing up your lower back, go for it. But few fitness trainers recommend old-style sit-ups, though there are some re-conceptualized versions of them that might work for you.
The question used to assess location of exercise had the following response options: home, outdoor in nearby area, nature, gym, indoor- and outdoor sports facility. Indoor- and outdoor sports facility was categorized as “sports facility” due to a low response rate on the outdoor sports facility option (1%). For social setting of exercise, the response options were: exercised alone, exercised together with others, and organized by Generation 100.
Before beginning any workout program, it’s always a good idea to consult your physician. Individuals with pre-existing injuries or medical conditions or those who don’t have an accurate knowledge of their current physical fitness level should always begin cautiously. It’s also extremely important to perform all workouts, no matter what fitness method you’re doing, under the supervision of a certified instructor. Their guidance and knowledge of proper form and technique will help you to achieve maximum results while avoiding injuries. They can also help you to safely modify workout activities to match your current fitness levels and goals. Whether you attend classes in a studio or at home through DVDs or streamed videos, the presence of a trained instructor is imperative.
Yet some of the best physical activities for your body don't require the gym or ask you to get fit enough to run a marathon. These "workouts" can do wonders for your health. They'll help keep your weight under control, improve your balance and range of motion, strengthen your bones, protect your joints, prevent bladder control problems, and even ward off memory loss.
Lie on your back with the knees bent and feet hip-width apart. Place arms at your side and lift up the spine and hips. Only the head, feet, arms, and shoulders should be on the ground. Then lift one leg upwards, keeping the core tight. Slowly bring the leg back down, then lift back up. Try to do 10 reps per leg, then bring the knee in place and spine back on the floor.
The exercises listed in Week 1 are a collection of basic moves that, while also used by advanced lifters, we feel are suitable for the beginner as well. Notice we’re not starting you off with only machine exercises; a handful of free-weight movements are present right off the bat. Reason being, these are the exercises you need to master for long-term gains in muscular size and strength, so you may as well start learning them now. Carefully read all exercise descriptions before attempting them yourself.
“Foam rolling is a form of massage (or trigger point release) that you can do to loosen tight muscles to help improve your mobility,” says Lefkowith. Using a foam roller helps smooth out “knots” in your fascia (the layer of connective tissue surrounding your muscles), which can get in the way of your range of motion. This is crucial for performing exercises with correct form and making sure the right muscle fibers are firing away. While you can stop, drop, and foam roll anytime, it’s often recommended to spend a few minutes with the foam roller before your workout to help get the juices flowing.
I saw the commercial for this program a few years ago on TV and laughed when it came on. I thought it was just another one of those infomercials that advertised something unattainable and absolutely ridiculous. Who could possibly get ripped by working out in their living room for an hour a day? Well, let's fast forward 3 years later to 2011 and I certainly wasn't laughing anymore. During my college years I managed to pack on 50 pounds of extra weight that needed to come off. So, I went on a diet and started working out at the local gym. Well, that whole gym thing didn't last long. Between gas prices and the membership cost, I just wasn't feeling it. While venting to one of my friends, he suggested that I do P90x. Needless to say he received an eyebrow raise from me. Fast forward another 2 weeks later ... full review
This reformer exercise is an efficient way to work the entire lower body.  Kneel on the reformer and round the back, keeping the arms straight. Use the butt muscles and thighs to push and pull your lower body back and forth. The platform will slide a few inches with each movement. Do five reps. As you get more advanced, do another five reps with the back arched.
Data were analysed using three different methods: visual inspection, parametric statistics and calculation of sensitivity for both OTS and NFO detection. Because the sample size was rather small (ie, maximal 5 for each group), data were first inspected visually. Parametric statistics and sensitivity calculation were used to support conclusions from visual inspection of the data. For the purpose of visual inspection, we created graphs with averages and SE for both the OTS and the NFO groups.
If you don't have access to weights, then you can perform resistance exercises utilizing just the weight of your own body. These types of exercises include pull ups, push ups, crunches, squats, and lunges. If you'd like to find a well designed workout using body weight resistance, try the Slow Burn Fitness Revolution, which relies on slow movements to really increase intensity as you perform isotonic exercises.
In 1912, Alexander claimed that the principles of ‘conscious control’ constitute an unfailing remedy for disease, including the cases of shortening of the spine, an injured arm, and a golfer who is practicing his swing.21 Pilates and Alexander [Internet]. Macy JA. Alexander Technique and the Pilates method of movement re-education: A biomechanical perspective. 2010 Dec 6 [cited 2015 Aug 30]. Available from: http://pilatesandalexander.com/articles/macy/. [Google Scholar] Alexander was against weightlifting, claiming that their focus on isolating muscles did not address the short- and long-term damage of impaired functional movements: ‘The physical body thus had two existences ... one fiercely active, muscular, dynamic, the other sedentary, nervous, static.’21 Pilates and Alexander [Internet]. Macy JA. Alexander Technique and the Pilates method of movement re-education: A biomechanical perspective. 2010 Dec 6 [cited 2015 Aug 30]. Available from: http://pilatesandalexander.com/articles/macy/. [Google Scholar] He allied himself with the turn of the 20th century MMB movement emergence:20 Alexander FM. Man's supreme inheritance. London: Methuen; 1910. [Google Scholar]
Just shy of an hour long, this video is a killer aerobic kickboxing workout. You’ll throw punches and kicks in supercharged sequences as you follow along with the ebullient Billy Blanks. Don’t be surprised if you start talking back to the screen, especially when Blanks looks straight into the camera and declares, “I see you at home! Keep going!” Talk about motivation.
Check your company's stock plan for the allowed methods and procedures. Once you do give notice to exercise with payment as required under your stock plan, it is unlikely that you can then change your decision to exercise or the exercise method, at least for tax purposes. This is illustrated by the case of Walter v. Commissioner, decided by the US Tax Court (TC Memo 2007-2, January 3, 2007). The employee attempted to change his original exercise instructions from a same-day sale to a cash exercise/hold. The Tax Court did not let him, holding that he had beneficial ownership of the stock when he initially exercised the options following the conditions under his stock plan.
Clean & Jerk: The other Olympic lift, the clean & jerk actually encompasses two separate movements. Athletes start by explosively lifting a weighted barbell from the ground to the shoulders, often squatting under and then standing to recover. After a brief pause, athletes take a shallow dip and then drive upward to propel the bar overhead, often landing in a split position and then bringing their feet back in line.
Alicia Marie, celebrity trainer, says you can change your core with plank twist corkscrews. “Hold in low plank position, keeping your core muscles tight and your forearms flat,” she says. “Slowly rotate your hips to one side, being sure not to drop them to the floor, then rotate your hips back to center. With your core muscles still engaged, rotate to the opposite side. Alternate back and forth slowly, completing five reps on each side for a total of four sets.”

Raphael AJ. Natural childbirth in twentieth century England; PhD thesis. London: Queen Mary University of London; 2010.  In the sub-continent, Vaughan was amazed that mostly affluent women suffered physically and mentally from childbirth, while poor women typically gave birth with relative ease. She explained that the active indigenous Indian lifestyle and regular exercises that maintain a functional pelvic anatomy were abandoned by the affluent.27 Vaughan K. The shape of the pelvic brim as the determining factor in childbirth. BMJ. 1931;2(3698):939–41.10.1136/bmj.2.3698.939[Crossref], [PubMed] [Google Scholar] Vaughan also observed that traditional Indian women, who covered their entire body with garments, were at risk of medical dangers including osteopenia due to sunlight deprivation.28 Vaughan KO. The purdah system and its effect on motherhood. Cambridge: W. Heffer & Sons Limited; 1928. [Google Scholar]

During your workout you have “target” heart rate zones that are expressed as a percentage of your max heart rate. For low-intensity cardio, you want to aim for 60 to 70 percent of your max heart rate, for moderate-intensity cardio the goal is 70 to 85 percent, and for high-intensity cardio, 85 percent or above. This can help you see if you’re really working as hard as you think you are and adjust as needed to make sure you’re hitting your workout goals. Here’s how to calculate your max and target heart rate zones.
Anaerobic exercise, which includes strength and resistance training, can firm, strengthen, and tone muscles, as well as improve bone strength, balance, and coordination.[3] Examples of strength moves are push-ups, pull-ups, lunges, and bicep curls using dumbbells.[3] Anaerobic exercise also include weight training, functional training, eccentric training, interval training, sprinting, and high-intensity interval training increase short-term muscle strength.[3][5]

Jump up ^ Olsen CM (December 2011). "Natural rewards, neuroplasticity, and non-drug addictions". Neuropharmacology. 61 (7): 1109–1122. doi:10.1016/j.neuropharm.2011.03.010. PMC 3139704. PMID 21459101. Similar to environmental enrichment, studies have found that exercise reduces self-administration and relapse to drugs of abuse (Cosgrove et al., 2002; Zlebnik et al., 2010). There is also some evidence that these preclinical findings translate to human populations, as exercise reduces withdrawal symptoms and relapse in abstinent smokers (Daniel et al., 2006; Prochaska et al., 2008), and one drug recovery program has seen success in participants that train for and compete in a marathon as part of the program (Butler, 2005). ... In humans, the role of dopamine signaling in incentive-sensitization processes has recently been highlighted by the observation of a dopamine dysregulation syndrome in some patients taking dopaminergic drugs. This syndrome is characterized by a medication-induced increase in (or compulsive) engagement in non-drug rewards such as gambling, shopping, or sex (Evans et al., 2006; Aiken, 2007; Lader, 2008).


Stand on right foot with left foot elevated and core tight. Hop 3 times then bend down and quickly walk hands out so you are in a high plank position with left foot still off ground. Do 3 push-ups, never putting left foot down. Walk hands back and stand up to return to starting position. Repeat for half the time on one side only, then switch sides.

Before anyone’s crowned Cap’n Crunch, remember form is key. Lie on your back with the knees bent and feet flat on the floor. With hands behind the head, place the chin down slightly and peel the head and shoulders off the mat while engaging the core. Continue curling up until the upper back is off the mat. Hold briefly, then lower the torso back toward the mat slowly.
Before beginning any workout program, it’s always a good idea to consult your physician. Individuals with pre-existing injuries or medical conditions or those who don’t have an accurate knowledge of their current physical fitness level should always begin cautiously. It’s also extremely important to perform all workouts, no matter what fitness method you’re doing, under the supervision of a certified instructor. Their guidance and knowledge of proper form and technique will help you to achieve maximum results while avoiding injuries. They can also help you to safely modify workout activities to match your current fitness levels and goals. Whether you attend classes in a studio or at home through DVDs or streamed videos, the presence of a trained instructor is imperative.
Go online for more information, recommends certified personal trainer Paula Zurowski. Web sites like collagevideo.com or Zurowski's exercisevideosreviews.com offer detailed descriptions and ratings of fitness videos. Collage even offers a one-minute clip of most videos, so you can get a feel for the level of the workout and whether you're going to like the instructor.
There are TONS of exercise videos on the market today and trying to decide which ones are good and which ones will just end up on the shelf unused. The three exercise video sets featured here are all on the top ten lists on review sites and customers love them. While they may not be good for every fitness level, they are challenging, they bring results and users love them.
Interval training is a type of training, which consists of alternating periods of high and low-intensity workouts interspersed with rest or relief periods. The high-intensity parts can be close to or in the anaerobic zone while the rest and relief periods involve lower intensity exercise. Interval training gets your rate up and burns more fat in less time than less intense forms of exercise. Here’s an example of an interval training routine:
Both groups exercised most frequently outdoors in nearby area and in nature (Fig. 5). Additional analyses showed that outdoors was the most frequently reported exercise location in both warmer (April–October) and colder (November–March) months. The MCT group had a significantly higher proportion of sessions outdoors than the HIIT group. Contrary, compared to the MCT group, HIIT had a higher proportion of sessions at a gym, sports facility and at home (Fig. 5).
Dancer, choreographer, stunt woman and fitness expert Kelly Connolly says you can shrink your waist in 30 seconds a day with “salsa swivels.” “It’s no secret that dancing is a great way to trim down and tone without even realizing you’re exercising,” she says. “The high energy and twisting motions of Salsa dancing can have a significant impact on your body while giving you some new moves to take to the dance floor.”
Along with prenatal vitamins and regular doctor’s appointment, The Bloom Method should be an essential part of your prenatal experience. Brooke’s knowledge and passion for pre and postnatal health and wellness is unmatched. Thanks to the regular workouts and the prenatal exercises that Brooke taught me, I feel amazing. The Bloom Method is a fundamental investment in baby and mommy’s health.

Multiple component community-wide campaigns are frequently used in an attempt to increase a population's level of physical activity. A 2015 Cochrane review, however, did not find evidence supporting a benefit.[122] The quality of the underlying evidence was also poor.[122] However, there is some evidence that school-based interventions can increase activity levels and fitness in children.[15] Another Cochrane review found some evidence that certain types of exercise programmes, such as those involving gait, balance, co-ordination and functional tasks, can improve balance in older adults.[123] Following progressive resistance training, older adults also respond with improved physical function.[124] Survey of brief interventions promoting physical activity found that they are cost-effective, although there are variations between studies.[125]
This stands for rate of perceived exertion, and refers to intensity. It’s a point of reference that trainers often use to communicate how hard you should be working since what feels easy or challenging is different for everyone. On the RPE scale a 1 pretty much means zero effort while a 10 means you’re working harder than you thought you possibly could.
As a "formerly advanced" climber who is trying to get back into a healthy regimen after a year or two off, this book was excellent review of some obvious components of active practice that I'd forgotten in my rush to get back to my old level of climbing. Horst continues to be the best when it comes to training guides. Cannot recommend this book (or any of the others) enough.
Alexander shared the main goal of other MMB pioneers, to harmonize normal functional movements; however, he differed in his approach of teaching the movements. According to the Alexander Technique, the development of nervous system control precedes the functional improvements, unlike other MMB schools in which the nervous system control is developed secondarily by doing the exercises in the proper manner.21 Pilates and Alexander [Internet]. Macy JA. Alexander Technique and the Pilates method of movement re-education: A biomechanical perspective. 2010 Dec 6 [cited 2015 Aug 30]. Available from: http://pilatesandalexander.com/articles/macy/. [Google Scholar] In 1914, Alexander expanded his teaching in New York and returned to England in 1925. By the end of his career, he had cultivated a long list of loyal second-generation teachers who preserved the Alexander Technique legacy and widespread acceptance until today.19,21 Staring J. Frederick Matthias Alexander 1869-1955. The Origins and History of the Alexander Technique. A medical historical analysis of F.M. Alexander’s life, work, technique, and writings. Nijmegen: Radboud Universiteit; 2005.
Even after long term IV therapy and other holistic type treatments to treat the Epstein Barr virus and co-infections in the blood, I still have CFS/ME. I have found effective ways to work with CFS/ME, yet this is not an overnight process and all of the lifestyle tools come into play even more so here. Visit our supplement page at anytime where we discuss options for immune support. Be sure you are getting enough zinc. This is sometimes overlooked. An additional 20-50 mg. can be helpful with CFS/ME. 

Indian yoga gurus started arriving to the West at the turn of the 20th century, however, yoga as it is known today only evolved as a popular method to ‘stay healthy and relaxed’ during the second half of the century.50 Syman S. The subtle body: the story of yoga in America. New York (NY): Farrar, Straus & Giroux; 2010. [Google Scholar] There was no contact found between the sporadic early yoga arrivals to the West and the MMB pioneers discussed within this research. However, Eastern mind–body practices profoundly influenced Randell and Morris, most probably via Vaughan, who had just returned from years of obstetric work and eye-opening behavioral observations in India prior to the inception of the St Thomas project in 1912.


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The severity of angina and the effects of therapeutic interventions in patients with coronary artery disease have been assessed by determining changes in both exercise performance and the triple product (TP) of heart rate, systolic pressure, and ejection time occurring at angina. However, the validity of conclusions based on such changes is uncertain since the effects of different exercise protocols on these variables have not been determined. Twelve patients with angina were studied during upright bicycle exercise; repeated bouts of exercise using a standard protocol of 20-w increments every three minutes produced no consistent changes in TP at angina. When exercise began 20 to 60 w above the work load of the standard protocol that produced angina, exercise capacity was reduced (average 1'40'' vs. 4'40'', P < 0.001), and triple product at angina exceeded control anginal values (average 4,840 vs. 4,150, P < 0.001). In the control studies nitroglycerin (TNG) and carotid sinus nerve stimulation (CSNS) enabled patients to exercise to a higher level, although the triple product at angina was unaltered. However, at the higher work load TNG and CSNS exerted only minimal effects on exercise capacity, indicating that if the work load is excessive, a reduction in myocardial oxygen consumption produced by a therapeutic intervention may be comparatively minor so that a potentially salutary effect would be masked. We conclude that work loads causing angina in less than three minutes cannot reliably be used for studying the effects of therapy. However, if progressive work loads are chosen which cause angina in the control studies in three to six minutes, exercise capacity and triple product at angina provide important information about the efficacy and mechanism of action of a therapeutic intervention.
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