The results of this study present evidence in favor of this high intensity OLDE protocol to investigate muscle fatigue and muscle endurance. Indeed, this new protocol developed in our laboratory i) presents a lower variability than other high intensity time to exhaustion tests [20], ii) is not limited by the cardiorespiratory system and iii) allows a quick start of neuromuscular testing to fully appreciate the extent of muscle fatigue induced by the exercise. Therefore, it can provide an interesting tool to isolate the cardiorespiratory and neuromuscular effects of various manipulations supposed to play a role in muscle fatigue and performance during high intensity dynamic endurance exercise (e.g. spinal blockade of afferent feedback from the working muscles).
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In healthy adults, aerobic exercise has been shown to induce transient effects on cognition after a single exercise session and persistent effects on cognition following regular exercise over the course of several months.[33][42][45] People who regularly perform aerobic exercise (e.g., running, jogging, brisk walking, swimming, and cycling) have greater scores on neuropsychological function and performance tests that measure certain cognitive functions, such as attentional control, inhibitory control, cognitive flexibility, working memory updating and capacity, declarative memory, spatial memory, and information processing speed.[33][37][39][41][42][45] The transient effects of exercise on cognition include improvements in most executive functions (e.g., attention, working memory, cognitive flexibility, inhibitory control, problem solving, and decision making) and information processing speed for a period of up to 2 hours after exercising.[45]

Thus, little is known about the effects of monitored vigorous exercise in elderly people. While significant benefits for basic motor tasks (such as balance and gait) can be achieved through different kinds of physical activity (i.e., stretching exercises, treadmill, Pilates, and strength and balance training), no conclusive relationship has been proven between its intensity and such improvements. Recently, Pau et al. [14] reported that spatiotemporal gait parameters and sit-to-stand performance significantly improve through vigorous (but not light) exercises, thus suggesting that higher levels of intensity might be more suitable in generally improving static and dynamic daily motor tasks.