Pharmacologic beta-adrenergic blockade reduces maximal heart rate (HR) during exercise but variable results have been reported for minute ventilation (VE), CO2 output (VCO2), and O2 uptake (VO2). A total group of 19 subjects with mild asthma was studied. We studied 16 subjects from the group who received placebo or pindolol, a beta-adrenergic antagonist, during 1-min incremental exercise on a ... [Show full abstract]Read more
'Time exposed' to training, in both the intervention and control arms of the study, was defined as the length of time an individual spent in training with his or her original training group free of AKP. Patients were thus censored at the point they were removed from training (various time-points through the 14-week training period). Participants who successfully completed training with their original troop were censored at the point of exit (14 weeks). There was no follow-up after the 14-week point.

Ten patients who consulted a sports physician with complaints of underperformance and fatigue participated in the present study. The eight men and two women had an average height and weight of 181±(8) cm and 68.4±(11.8) kg. All subjects were diagnosed by a sports physician according to the latest guidelines for overtraining diagnosis.1 18 A careful history including training history was taken, completed by a physical examination and a blood draw to rule out other possible causes for the complaints. Patients were diagnosed as NFO or OTS retrospectively according to the severity of symptoms and the total duration of symptoms and underperformance (ie, both before and after testing) when no medical explanation for the condition could be found. It turned out that a cutoff of 1-year total duration gave a good distinction between NFO and OTS patients. Demographic data and reported symptoms can be found in table 1. Data of subject 1 are the same as presented in an earlier publication.10 All subjects signed informed consent before participation.
^ Jump up to: a b McKee AC, Daneshvar DH, Alvarez VE, Stein TD (January 2014). "The neuropathology of sport". Acta Neuropathol. 127 (1): 29–51. doi:10.1007/s00401-013-1230-6. PMC 4255282. PMID 24366527. The benefits of regular exercise, physical fitness and sports participation on cardiovascular and brain health are undeniable ... Exercise also enhances psychological health, reduces age-related loss of brain volume, improves cognition, reduces the risk of developing dementia, and impedes neurodegeneration.
Resting hormone concentrations have been a topic of many studies and discussions. It has been suggested that conflicting results were, at least partly, because of a lack of standardisation in both the way overtraining was measured and in the hormone measurement protocols used. Results from the present study show that variability in resting hormone concentrations is also present within groups of NFO and OTS patients. The arguments for contradictory findings are not valid within this study where blood was drawn at the same time of day always after an overnight fast. However, the diurnal variation in cortisol cannot be ruled out with this protocol because tests are separated by 4 h. However, each test was done with the same protocol and timing so that the data were collected in a standardised manner. One possible reason why the cortisol levels do not show the same pattern as ACTH might be because of this diurnal variation. Therefore, it must be concluded that resting hormone concentrations are not sensitive enough, at least not to diagnose unexplained underperformance in athletes. It has been suggested that hormonal reactions to stress tests are more sensitive.1 11
The lateral raise (or shoulder fly) is performed while standing or seated, with hands hanging down holding weights, by lifting them out to the sides until just below the level of the shoulders. A slight variation in the lifts can hit the deltoids even harder, while moving upwards, just turn the hands slightly downwards, keeping the last finger higher than the thumb. This is an isolation exercise for the deltoids. Also works the forearms and traps.

The hypothalamus is under the control of several “higher” brain centres and several neurotransmitters 13 known to play a major role in various neuroendocrine and behavioural functions, for example, activation of the HPA axis, feeding and locomotion.14 Therefore, the typical HPA axisrelated hormones cortisol, adrenocorticotrophic hormone (ACTH), prolactin (PRL) and human growth hormone (GH) were targeted in the present study.

Whenever I’m feeling overwhelmed and super busy, the first thing that always falls off my schedule is hitting the gym—even though I know making the extra time to sweat it out will make me feel better and more centered. But I’ve realized that you can always find a way to prioritize the things that matter, even if you have to get creative with the way you fit them in.
Yoga also offers many mental benefits, such as a reduction in stress level. Greater relaxation and reduced stress leads to a host of other positive body changes including an improvement in circulation, sleep and self-confidence. A positive mental outlook also helps to maintain a healthy immune system, which in turn can ward off other serious ailments such as high cholesterol, heart disease and stroke.

Exercise tests were performed on a cycle ergometer (Lode Excalibur Sport, Groningen, The Netherlands) or on a treadmill (Ergo ELG 55; Woodway, Weil am Rhein, Germany) depending on the sport. Tests on the cycle ergometer started with an initial workload of 80 W (subjects 6 and 7) or 30 W (subjects 4 and 9), the workload was increased by 40 W every 3 min. Tests on the treadmill started at 5.4 km h−1, the speed was increased with 1.8 km h−1 each 3 min (subjects 1, 2, 3, 8 and 10). One subject performed the treadmill test with an inclination of 1% (subject 5). The duration of each test was recorded in seconds. Subjects wore a heart rate monitor (Polar Accurex Plus, Kempele, Finland) for determination of maximal heart rate (HRmax) throughout the exercise tests. After each exercise test, 20 μl of blood was drawn from the right earlobe to determine maximal blood lactate concentration ([La]max) with enzymatic analysis (EKF; Biosen 5030, Barleben, Germany).

First, we must follow the same guidelines and general protocols for building a stronger ‘foundation’ as we have outlined in the fibromyalgia protocol articles here on this website. The idea is to build a stronger core and immune status. After we have created a support system for the immune and nervous system involvement, we can begin to incorporate an exercise program best suited for fibromyalgia chronic fatigue syndrome.


Now that you understand the vast amount of categories available to you, you can start narrowing the field of choices down by looking at the specifics of exercise videos and deciding which ones will be something you will not only enjoy but continue to use long term. If you are starting out as a beginner to exercise, then you should expect to upgrade your exercise videos as your fitness levels increase. You don’t have to stay with a beginner video when your fitness level advances to intermediate or advanced. Below are some factors to look at when looking at individual videos.
One remedy for the exercise doldrums is to keep exploring new types of movement, even if you’re already committed to a particular form of exercise. Novel activities — dance, martial arts, outdoor exercise — can work wonders for your brain, your mood, and your fascia. Massage, Rolfing, Feldenkrais, foam rolling, and other bodywork modalities can keep these tissues supple, too, so you can continue to move well, and without pain, for decades to come.
Who says you have to jump, grunt, strain and punish your body to get amazing results from your workout? Not with PiYo. PiYo combines the muscle-sculpting, core-firming benefits of Pilates with the strength and flexibility advantages of yoga. And, we crank up the speed to deliver a true fat-burning, low impact workout that leaves your body looking long, lean and incredibly defined.

Jump up ^ Petersen RC, Lopez O, Armstrong MJ, Getchius T, Ganguli M, Gloss D, Gronseth GS, Marson D, Pringsheim T, Day GS, Sager M, Stevens J, Rae-Grant A (January 2018). "Practice guideline update summary: Mild cognitive impairment – Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology". Neurology. Special article. 90 (3): 1–10. doi:10.1212/WNL.0000000000004826. PMID 29282327. Lay summary – Exercise may improve thinking ability and memory (27 December 2017). In patients with MCI, exercise training (6 months) is likely to improve cognitive measures and cognitive training may improve cognitive measures. ... Clinicians should recommend regular exercise (Level B). ... Recommendation


What are your fitness goals? – Do you want to tone up? Lose fat and inches? Gain lean muscle mass? Maintain your weight? Reshape Your body? There are a number of fitness goals you could be interested in and many people have more than one, for example they want to lose fat and inches AND reshape their bodies. What your fitness goals are can determine the type of exercise videos that will fit those needs and goals the best.

Along with prenatal vitamins and regular doctor’s appointment, The Bloom Method should be an essential part of your prenatal experience. Brooke’s knowledge and passion for pre and postnatal health and wellness is unmatched. Thanks to the regular workouts and the prenatal exercises that Brooke taught me, I feel amazing. The Bloom Method is a fundamental investment in baby and mommy’s health.


Former ballet dancer and Ballet Beautiful founder Mary Helen Bowers has serious fitness cred thanks to training Natalie Portman for her role in Black Swan. With this free workout video, she takes her expertise outside the dance studio. The 15-minute mat workout will help tone your lower body with graceful ballet-inspired movements like bridge variations.
If you've been to yoga before, you'll recognize this as a near chaturanga—but a little faster. Start in a down dog position with hands on the ground, hips high in the air, and feet on the ground so you form a triangle shape. In a fluid motion, dive head toward the floor, coming into a low push-up position, and then swoop chest forward and up so you end in an upward dog position. From there, push hips up to return to starting position.
The deadlift is a very effective compound exercise for strengthening the lower back, but also exercises many other major muscle groups, including quads, hamstrings and abdominals. It is a challenging exercise, as poor form or execution can cause serious injury.[8] A deadlift is performed by grasping a dead weight on the floor and, while keeping the back very straight, standing up by contracting the erector spinae (primary lower back muscle). When performed correctly, the role of the arms in the deadlift is only that of cables attaching the weight to the body; the musculature of the arms should not be used to lift the weight. There is no movement more basic to everyday life than picking a dead weight up off of the floor, and for this reason focusing on improving one's deadlift will help prevent back injuries.
This Chinese martial art that combines movement and relaxation is good for both body and mind. In fact, it's been called "meditation in motion." Tai chi is made up of a series of graceful movements, one transitioning smoothly into the next. Because the classes are offered at various levels, tai chi is accessible — and valuable — for people of all ages and fitness levels. "It's particularly good for older people because balance is an important component of fitness, and balance is something we lose as we get older," Dr. Lee says.
I must confess: the title of this section is misleading, because while most of us associate the first home workouts with fitness icons Jane Fonda and Richard Simmons, they were not the first ones to bring workouts inside our homes. In fact, before there were VHS tapes, before there were even televised workouts, there were the audio-only vinyl record workouts, nicknamed vinylcise.
Your body has that whole breathing thing on lock, but there's more than one way to inhale and exhale and some require extra work from the abs. "Kapalabhati breathing engages the transverse abdominis to push out the breath," says Allison Candelaria, owner of Soul Yoga in Oklahoma City. Here's how to do it: Sit tall, then strongly and quickly pull your navel toward your spine. Then release your ab muscles, forcing you to exhale. Work up to doing that 20 times, inhaling and letting your belly expand between each "pump." (This belly bonfire breathing technique can also help you fire up your body anywhere, anytime.)
Improving your balance makes you feel steadier on your feet and helps prevent falls. It's especially important as we get older, when the systems that help us maintain balance—our vision, our inner ear, and our leg muscles and joints—tend to break down. "The good news is that training your balance can help prevent and reverse these losses," says Wilson.
Continuous aerobic exercise can induce a transient state of euphoria, colloquially known as a "runner's high" in distance running or a "rower's high" in crew, through the increased biosynthesis of at least three euphoriant neurochemicals: anandamide (an endocannabinoid),[73] β-endorphin (an endogenous opioid),[74] and phenethylamine (a trace amine and amphetamine analog).[75][76][77]
“Foam rolling is a form of massage (or trigger point release) that you can do to loosen tight muscles to help improve your mobility,” says Lefkowith. Using a foam roller helps smooth out “knots” in your fascia (the layer of connective tissue surrounding your muscles), which can get in the way of your range of motion. This is crucial for performing exercises with correct form and making sure the right muscle fibers are firing away. While you can stop, drop, and foam roll anytime, it’s often recommended to spend a few minutes with the foam roller before your workout to help get the juices flowing.

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These may be your go-to lower-body moves, but if you do them mindfully—and with dumbbells—squats can double as an ab-firming opportunity. "When you lower into a squat, you have to draw the navel in and activate your pelvic floor to protect the lower back, and then you squeeze the glutes to rise, which are part of your core as well," says celebrity trainer Kira Stokes, creator of the Stoked Method workouts. Up the ante by holding weights or a bar overhead or across your shoulders in front of your body. (Kick your squats into high gear with these 16 booty-boosting squats.)
Stand on right foot with left foot elevated and core tight. Hop 3 times then bend down and quickly walk hands out so you are in a high plank position with left foot still off ground. Do 3 push-ups, never putting left foot down. Walk hands back and stand up to return to starting position. Repeat for half the time on one side only, then switch sides.

Jump up ^ Linke SE, Ussher M (2015). "Exercise-based treatments for substance use disorders: evidence, theory, and practicality". Am J Drug Alcohol Abuse. 41 (1): 7–15. doi:10.3109/00952990.2014.976708. PMC 4831948. PMID 25397661. The limited research conducted suggests that exercise may be an effective adjunctive treatment for SUDs. In contrast to the scarce intervention trials to date, a relative abundance of literature on the theoretical and practical reasons supporting the investigation of this topic has been published. ... numerous theoretical and practical reasons support exercise-based treatments for SUDs, including psychological, behavioral, neurobiological, nearly universal safety profile, and overall positive health effects.
Include strength training at least 2 days per week. Also known as resistance training, strength training involves using free weights, resistance bands, or your own body weight to strengthen your muscles. If you’re just starting out, try doing upper and lower body workouts 1 day a week each. In time, gradually work your way up to including 3 to 4 strength training days in your weekly routine.[4]
The deadlift is a very effective compound exercise for strengthening the lower back, but also exercises many other major muscle groups, including quads, hamstrings and abdominals. It is a challenging exercise, as poor form or execution can cause serious injury.[8] A deadlift is performed by grasping a dead weight on the floor and, while keeping the back very straight, standing up by contracting the erector spinae (primary lower back muscle). When performed correctly, the role of the arms in the deadlift is only that of cables attaching the weight to the body; the musculature of the arms should not be used to lift the weight. There is no movement more basic to everyday life than picking a dead weight up off of the floor, and for this reason focusing on improving one's deadlift will help prevent back injuries.
Making the commitment to start an exercise program is an exciting first step in improving your life through increased physical and mental health. After all, what better investment can you make than in yourself? If you’ve struggled with not having enough time, money, energy or motivation to work out, push them aside and remember that you’re worth it. No excuses!
Spark People shares short videos for all different types of workouts. There are several categories -- Abs, Cardio, Yoga and Pilates, as well as others that diver into healthy cooking and eating ideas. These workouts are great when you are pinched for time. Choose a 10-12 minute routine and squeeze in some activity where you normally would have skipped it altogether.
Workouts are an extremely efficient experience for our clients. You will be in and out in less than 30 minutes. You will come in no more than twice per week. Don't worry, that's all the time we need to target all major muscle groups and the cardiovascular system. Our instructors set up the equipment, keep detailed notes, and guide our clients through every step of the workout.
In healthy adults, aerobic exercise has been shown to induce transient effects on cognition after a single exercise session and persistent effects on cognition following regular exercise over the course of several months.[33][42][45] People who regularly perform aerobic exercise (e.g., running, jogging, brisk walking, swimming, and cycling) have greater scores on neuropsychological function and performance tests that measure certain cognitive functions, such as attentional control, inhibitory control, cognitive flexibility, working memory updating and capacity, declarative memory, spatial memory, and information processing speed.[33][37][39][41][42][45] The transient effects of exercise on cognition include improvements in most executive functions (e.g., attention, working memory, cognitive flexibility, inhibitory control, problem solving, and decision making) and information processing speed for a period of up to 2 hours after exercising.[45]
For active types, nagging injuries nag a little louder; hard workouts deplete you a bit more. For serious recreational athletes, performance begins to drop, even if you maintain your training regimen. Whatever your sport of choice — be it distance running, competitive cycling, or pick-up basketball — you can expect your performance to plateau and recovery to take a bit longer.
To try it, choose a medium-heavy weight (50 percent to 70 percent of your one-rep-max, or 1RM, if you know it). Lift it with as much velocity as you can muster, then lower it with control. For instance, if you are bench pressing, the push up will feel almost as though you are punching the weight up into the ceiling. Once you have completed the lift, slowly lower the weight to your chest. You can apply this technique using a variety of implements, including dumbbells, barbells, weight machines, elastic bands, and body weight, he explains.
"Look for something with a lot of short segments," says Neporent. "This way, you can do a 10-minute set and you're not committed to a longer routine." When you're ready, you can add the segments together and the workout will still flow. DVD technology has made it easier for video exercisers to do short segments or put several together, depending on their ability
A Polar (www.polar.fi) heart rate monitor (belt and watch) is used to measure heart rate continuously. A transmitter belt is fastened around the chest while the watch is held by a nearby observer. If at any time during the experiment the heart rate exceeds the predetermined ceiling (85% of age-predicted max heart rate) the experiment should be stopped immediately.
Mixing up your workout routine from time to time is very important for avoiding the dreaded plateau which is basically your body’s way of saying “I’m bored!” and it’s a big issue with a lot of people who have been on the same workout routine or fitness program for a while and really aren’t seeing the results they want. Your body needs stimulus from a variety of sources which includes everything from different reps and sets schemes to various training styles. If you’re struggling with building muscle mass or you’re having a difficult time losing body fat, then your primary goal should be to mix it up a little and start adding variety into your routines. By doing this you can truly shock your body into change since it will be receiving new stimuli from different sources. Use our extensive exercise guides on this page as a roadmap to help you reach your fitness and physique goals!
Target your glutes and core muscles with bridges. Lie on your back with your knees bent, feet flat on the floor, and your arms by your sides. Inhale, then exhale as you engage your core muscles and slowly raise your hips and lower back off of the floor. Lift yourself until your shoulders and knees form a straight line, and keep your arms flat on the floor to keep your balance.[19]
Making the commitment to start an exercise program is an exciting first step in improving your life through increased physical and mental health. After all, what better investment can you make than in yourself? If you’ve struggled with not having enough time, money, energy or motivation to work out, push them aside and remember that you’re worth it. No excuses!
Preliminary evidence from a 2012 review indicated that physical training for up to four months may increase sleep quality in adults over 40 years of age.[78] A 2010 review suggested that exercise generally improved sleep for most people, and may help with insomnia, but there is insufficient evidence to draw detailed conclusions about the relationship between exercise and sleep.[79]
Raphael AJ. Natural childbirth in twentieth century England; PhD thesis. London: Queen Mary University of London; 2010.  In the sub-continent, Vaughan was amazed that mostly affluent women suffered physically and mentally from childbirth, while poor women typically gave birth with relative ease. She explained that the active indigenous Indian lifestyle and regular exercises that maintain a functional pelvic anatomy were abandoned by the affluent.27 Vaughan K. The shape of the pelvic brim as the determining factor in childbirth. BMJ. 1931;2(3698):939–41.10.1136/bmj.2.3698.939[Crossref], [PubMed] [Google Scholar] Vaughan also observed that traditional Indian women, who covered their entire body with garments, were at risk of medical dangers including osteopenia due to sunlight deprivation.28 Vaughan KO. The purdah system and its effect on motherhood. Cambridge: W. Heffer & Sons Limited; 1928. [Google Scholar]
"CrossFit differentiates itself by being constantly varied in both movements and time domains," Mandelbaum says. "You might have a day in the box with a four-minute sprint workout one day, and then come in the next day for a 15-minute moderate-to-fast-paced workout featuring three movements that need to be repeated in a cycle or round until the time clock runs out."
Both groups performed an equal proportion of exercise sessions alone (MCT: 50%, HIIT: 49.6%) and together with others (MCT: 50%, HIIT: 50.4%). In both groups, women had a significantly higher proportion of sessions together with others compared to men (56% vs. 44%, p < 0.01). The HIIT group had a significantly higher proportion of sessions organized by Generation 100 compared to the MCT group (8.1% vs. 5.9%, p < 0.01).
If you haven’t strength trained regularly, muscle loss may now reach critical levels, interfering with balance, gait, and other daily activities. But if you take up strength training, those changes are reversible: A number of studies including adults in their 70s have found that progressive strength training two or three times per week can lead to such improvements as increased muscle mass, more ease with everyday activities like climbing stairs and carrying groceries, and reduced joint pain.

So, for me, squatting while commuting or planking (one of the 7 Best Ab Exercises for Women!) before bed has become quick and foolproof ways to make sure I get some part of my workout in without having to stress about making time for the gym. Instead, I bring the working out with me even on the go. Everyone has at least 30 spare seconds (trust me, even the days you’re sure you don’t—you do). That’s why I went to the experts and compiled a master list of exercises that work every body part. Best of all? Each one brings results if you do them for 30 seconds every day (some ask for 60 seconds, but that’s so you can work both arms and both legs). Just remember to keep your diet on track, too; just because you squeeze in mini workouts doesn’t mean you can feast on foods like these 20 Shocking Foods With More Fat Than a Big Mac!
Who says you have to jump, grunt, strain and punish your body to get amazing results from your workout? Not with PiYo. PiYo combines the muscle-sculpting, core-firming benefits of Pilates with the strength and flexibility advantages of yoga. And, we crank up the speed to deliver a true fat-burning, low impact workout that leaves your body looking long, lean and incredibly defined.
The daily practice of the mind–body exercises took only a few minutes, to blend in with modern life rather than to dominate it. The exercises could be performed in private with no competitive, commercial, or political emphasis or personal ignominy. The MMB pioneers were against unnatural purpose-made exercise machinery, which was viewed as unnecessary and even dangerous. An exception was Pilates and his equipment. However, the revolutionary devices were designed (and succeeded) to improve the effect of Contrology exercises and philosophy, and to enhance the method’s natural experience and acceptance.
One of the easiest parts of starting an exercise program is deciding to do it. Usually there's something inspiring you to make a change: Maybe you tried on a pair of jeans that were too tight or there's an upcoming event—a reunion, wedding, or party—where you're going to see people you haven't seen in a while. Whatever it is, you're motivated, you're excited, and the fantasy of a new, slimmer you is enough to inspire you.
Various weighted dumbbells. Some exercises require heavier weights, while others will need lighter weights or none at all. Try to have a range of dumbbells: a light set (3 to 5 pounds for women, 5 to 8 pounds for men), a medium set (5 to 10 pounds for women, 10 to 15 pounds for men), and a heavy set (10 to 20 pounds for women, 15 to 30 pounds for men).
This is the first review to have focused on exercise as an add-on strategy in the treatment of MDD. Our findings corroborate some previous observations that were based on few studies and which were difficult to generalize.41,51,73,92,93 Given the results of the present article, it seems that exercise might be an effective strategy to enhance the antidepressant effect of medication treatments. Moreover, we hypothesize that the main role of exercise on treatment-resistant depression is in inducing neurogenesis by increasing BDNF expression, as was demonstrated by several recent studies.
They’re fun and easy to do: Keep your upper body facing forward while your lower body moves; start with 10 swivels to the right, then 10 to the left. Then do 9 swivels to the right, 9 to the left, then 8 right 8 left, and so on down to one. As each set has your upper body twisting faster and faster, you should feel your abdominal muscles burning and your hips getting loose.
Overweight children who participate in physical exercise experience greater loss of body fat and increased cardiovascular fitness. According to the Centers for Disease Control and Prevention in the United States, children and adolescents should do 60 minutes or more of physical activity each day.[133] Implementing physical exercise in the school system and ensuring an environment in which children can reduce barriers to maintain a healthy lifestyle is essential.
Let’s just call this the accelerated beginner’s guide to bodybuilding. In this plan, your first month of training will be demanding, but not so demanding as to cause injury (or worse yet, burnout), and progressive in the sense that each week you’ll graduate to different exercises, higher volume, more intensity or all of the above. After four weeks you’ll not only be ready for the next challenge but you’ll have built a significant amount of quality muscle. In other words, one month from now you’ll look significantly better with your shirt off than you look now. (How’s that for results?)
Bonds H. The politics of the male body in global sport - the Danish involvement. Oxon: Routledge; 2010.  He regularly exposed his physique publicly and famously demonstrated his exercises and outdoor activities wearing a loincloth, including skiing St Moritz.17 Wildman S. Kafka's Calisthenics. Slate [Internet]. 2011 Jan 21 [cited 2015 Aug 30]. Available from: http://www.slate.com/articles/life/fitness/2011/01/kafkas_calisthenics.html. [Google Scholar] He stated:15 Müller JP. My system. London: Link House; 1904. [Google Scholar]
Stephanie Mansour, weight loss and lifestyle coach for women, has a great way to get your triceps toned while you’re watching TV. Just do 30 tricep dips on your couch. Here’s how: “Hands on edge of couch, fingers facing you. Bend your knees at 90-degree angle, scooting your butt up so it almost touches the couch,” she says. “Bend at the elbows, lower your body down, then press back up and straighten your arms. Repeat for 30 seconds to work on arm flab.”
In fig 3A–D, absolute hormone concentrations are presented for the NFO and the OTS groups. Visual inspection of the data led to the conclusion that resting concentrations cortisol, ACTH and PRLwere higher for OTS patients comparedwithNFO. However, reactions to exercise tests did not differ between the groups. Resting hormone concentrations were tested with independent t tests. Only for ACTH, the t test gave a value >2 (ie, t8=2.6; p<0.05), meaning that only for ACTH, the difference between the groups was more than twice as large as the SE. Sensitivity of resting cortisol, ACTH and PRL was four out of five (cutoff 175 μg l−1), four out of five (cutoff 40 ng l−1) and two out of five (cutoff 50 IU l−1), respectively (table 2). Sensitivity for detection of NFO was three out of five, four out of five and three out of five respectively for cortisol, ACTH and PRL, respectively (table 2).
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