Video Abstract for the ESSR 46.2 article “Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle With Aging” from author Donato Rivas. Age-induced loss of skeletal muscle mass and function, termed sarcopenia, may be the result of diminished response to anabolic stimulation. This review will explore the hypothesis that alterations in the expression of microRNA with aging contributes to reduced muscle plasticity resulting in impaired skeletal muscle adaptations to exercise-induced anabolic stimulation.
The relation between the increase in oxygen uptake (VO2) and increase in work rate (WR) between unloaded pedaling and maximal work during incremental cycle ergometer exercise was studied in normal men, men with uncomplicated systemic hypertension and ambulatory men with various cardiovascular diseases. The postulation was that impaired peripheral oxygen delivery would reduce the ratio of the ... [Show full abstract]Read more
^ Jump up to: a b Kyu, Hmwe H; Bachman, Victoria F; Alexander, Lily T; Mumford, John Everett; Afshin, Ashkan; Estep, Kara; Veerman, J Lennert; Delwiche, Kristen; Iannarone, Marissa L; Moyer, Madeline L; Cercy, Kelly; Vos, Theo; Murray, Christopher J L; Forouzanfar, Mohammad H (9 August 2016). "Physical activity and risk of breast cancer, colon cancer, diabetes, ischemic heart disease, and ischemic stroke events: systematic review and dose-response meta-analysis for the Global Burden of Disease Study 2013". BMJ. 354: i3857. doi:10.1136/bmj.i3857. PMC 4979358. PMID 27510511.
Ken Hutchins' analysis is not just book theory; it is based on real experience training many, many thousands of subjects over a span of decades. He trained everyone from amateur and professional level athletes and bodybuilders to little old ladies with osteoporosis and also a great many genetically normal/average folks. He assisted Arthur Jones and Ellington Darden at Nautilus Sports Medical Industries where he first refined the Superslow method during a 5 years long clinical trial, the Nautilus Osteoporosis Study at The University of Florida Medical School in Gainesville (the study is mentioned in chapter 8 of the 1990 edition of "The Nautilus Book" by Ellington Darden, a book I highly recommend for beginning HIT practitioners). Hutchins' writing is as dry and clinical as one would expect to find in any textbook about medicine or engineering. It is also filled with rich insight into the intellectual processes and long history of carefully controlled experiments at Nautilus (and later Hutchins' own facilities) that brought Ken Hutchins to his current level of knowledge. His understanding of anatomy, biology, physics, engineering, psychology, history and sociology are all put to good use in this book and should enthrall any reader that possesses solid critical-thinking skills. Understanding the arguments for a distinction of "Exercise vs. Recreation", "The First Definition of Exercise" and "Requirements for Functional Ability" are crucial for everyone that cares even the slightest about the subject of human health, fitness, longevity or quality of life. These are not trivial matters.
Jump up ^ Rhodes, J. S; Van Praag, H; Jeffrey, S; Girard, I; Mitchell, G. S; Garland Jr, T; Gage, F. H (2003). "Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running". Behavioral Neuroscience. 117 (5): 1006–16. doi:10.1037/0735-7044.117.5.1006. PMID 14570550.
Pregnant women may find yoga to be a beneficial workout, but you should always consult your physician before engaging in any exercise program, especially during pregnancy. Individuals who want a more relaxing form of exercise while improving upon their current level of fitness will find yoga to be enjoyable. Many people benefit from the clear-headedness that comes with the deep breathing and mind-calming exercises that take place with yoga.
Exercise duration, HRmax and [La]max are presented in fig 2A, B, and C. Visual inspection of the data led to the conclusion that there is no difference in exercise duration and HRmax between the OTS and the NFO patients. For [La]max, a much lower value was found for the OTS patients in combination with a larger reduction from the first to the second test compared with the NFO patients. However, parametric analysis did not indicate significant differences. The main effect of group gave an F ratio of 2.9 for [La]max and an F ratio <1 for exercise duration and HRmax, showing that almost three times as much variance is explained by the group membership (ie, OTS vs NFO) compared with random factors. In addition, sensitivity for OTS detection with [La]max was high (table 2). With a cutoff of 8 mmol l%#x2212;1, four out of the five OTS patients would have been diagnosed correctly from the first exercise test and four out of the four OTS patients from the second exercise test. Sensitivity for NFO diagnosis was lower, however (table 2). From the first exercise test, a correct diagnostic ratio of two out of four was found, for the second test, two out of three.
In the fourth and final week of the program, you’ll train four days in a four-way split that hits each bodypart just once (except for calves and abs, which are each trained twice). Four-day splits are common among experienced lifters because they involve training fewer bodyparts (typically 2–3) per workout, which gives each muscle group ample attention and allows you to train with higher volume. As you’ll see, chest and triceps are paired up, as are back with biceps and quads with hamstrings, each a very common pairing among novice and advanced bodybuilders. Shoulders are trained more or less on their own, and you’ll alternate hitting calves and abs—which respond well to being trained multiple times per week—every other workout. No new exercises are introduced in Week 4 so that you can focus on intensity in your workouts instead of learning new movements.
Upgrading physical fitness is a metabolically expensive process that requires sufficient time. After a "request" that adaptive changes be made, the human body needs recovery time to effect those changes, and for repair and replenishment. Exercising too often serves only to interrupt the recovery phase, further drain bodily resources, and hinders improved physical fitness. Exercising once every seven days is enough exercise to improve and maintain your level of fitness. More is not necessarily better when it comes to exercise... more is better when it comes to recovery. Think about it, since you don't know the precise moment recovery is completely finished, you will work out again either before recovery is done or after it is done. Common sense would dictate that it's better to wait until recovery is definitely finished before another intense workout is performed, which means you should be working out after you're done recovering. If you work out a few days before you should have, you will interfere with your recovery. If you work out a few days after you could have, you will not lose anything you've gained thus far.
Congratulations on your decision to make yourself a priority and commit to a regular workout routine. The addition of physical fitness into your life requires hard work, but yields great rewards. Now, which method should you choose? With the vast choice of fitness workout options available today, it can be overwhelming to know which one is right for you.
If you want to form a gym habit, it can be difficult to know what to do or how to workout. Once you become immersed in exercise, it can feel like there’s not enough time to try all the different things! Plain and simple, this is just a knowledge gap. Learning how to workout is like learning anything else, it requires time, research and study. Hiring a personal trainer is the fastest route around this, but it also helps to be a “student of the game” by continuing to educate yourself.
CrossFit Games: The sport of fitness has arrived (or so claims Reebok, the official sponsor of the CrossFit Games). Each summer the CrossFit Games test participants with a barrage of physical challenges and workouts, ranging from swimming and running to pull-ups and handstand walks (sorry, Kobayashi, hot-dog eating has yet to make an appearance). Participants accrue points over the events, and the male and female winners are crowned World’s Fittest Man & Woman. Sectional and Regional qualifiers narrow the field before the annual Games Weekend.
The benefits of exercise have been known since antiquity. Dating back to 65 BCE, it was Marcus Cicero, Roman politician and lawyer, who stated: "It is exercise alone that supports the spirits, and keeps the mind in vigor."[143] Exercise was also seen to be valued later in history during the Early Middle Ages as a means of survival by the Germanic peoples of Northern Europe.[144]
* Respect the body's design when exercising. We are capable of doing many things the body was not designed to do. And this is also true when it comes to physical activity. We're designed to walk, climb, and sprint. We walked a lot back in the good old days when we foraged in paradise, we climbed to get the sweetest fruit, and we occasionally sprinted to escape danger. Take a cue from little kids: they love to climb, when they run they sprint (try to get them to do distance running), and they can walk just fine. When we do the activities we're designed to do, that's when we'll be in great shape... we won't be under-active, and we won't be over-active, and both are bad for the body, for different sets of reasons.

I've always wanted to try out the trendy fitness classes at Physique 57 in NYC, but they run a pretty penny. Now, the infamous Physique 57 technique (certain muscles are targeted, overloaded to point of fatigue and then stretched for relief) is available to all in this 30-minute workout. It was just enough to make me realize why people are obsessed with the classes and left me — especially my glutes — sore the next day.


I read "Superslow: The Ultimate Exercise Protocol" back in 2000. Then relatively new to learning about exercise and bodybuilding I found it to be a truly fascinating and very challenging read. Not only was the material challenging in the intellectual sense but also in a philosophical sense. It was turning much of what I believed about "exercise" upside down. So meatheads and gym-rats be warned, "Superslow" is a highly technical book that the typical bodybuilder or exercise enthusiast would find "boring" (see other reviews here on Amazon) because it isn't full of ridiculous promises about gigantic, ripped muscles and marketing jargon for selling supplements. What it is is a very thorough analysis of the variety of benefits one can derive (regardless of their limited genetics) from properly performed exercise and the many proven pitfalls associated with a low-intensity and high workload/volume. The book also provides an in-depth history lesson on the continually evolving refinements to Arthur Jones' Nautilus principles. Hutchins' dogged determination to continually seek a safer and more effective way for people to exercise is admirable and shows his devotion to sound scientific principles.
If you've been to yoga before, you'll recognize this as a near chaturanga—but a little faster. Start in a down dog position with hands on the ground, hips high in the air, and feet on the ground so you form a triangle shape. In a fluid motion, dive head toward the floor, coming into a low push-up position, and then swoop chest forward and up so you end in an upward dog position. From there, push hips up to return to starting position.
With today’s demanding lifestyles, many individuals find it difficult to stick with a regular exercise program. The most common barriers to regular physical activity include lack of time and motivation. Other reported challenges include fear of injury, feelings of self-consciousness or not being athletic enough, and memories of perceived failure with prior exercise programs. Fortunately, many fitness studios offer free trials, flexible class times and even downloadable or streamed classes, so it’s easier than ever to commit.
This reformer exercise is an efficient way to work the entire lower body.  Kneel on the reformer and round the back, keeping the arms straight. Use the butt muscles and thighs to push and pull your lower body back and forth. The platform will slide a few inches with each movement. Do five reps. As you get more advanced, do another five reps with the back arched.
Jump up ^ Gomez-Pinilla F, Hillman C (January 2013). "The influence of exercise on cognitive abilities". Compr. Physiol. 3 (1): 403–428. doi:10.1002/cphy.c110063. ISBN 9780470650714. PMC 3951958. PMID 23720292. Abundant research in the last decade has shown that exercise is one of the strongest promoters of neurogenesis in the brain of adult rodents (97, 102) and humans (1,61), and this has introduced the possibility that proliferating neurons could contribute to the cognitive enhancement observed with exercise. In addition to BDNF, the actions of IGF-1 and vascular endothelial growth factor (VEGF) (54) are considered essential for the angiogenic and neurogenic effects of exercise in the brain. Although the action of exercise on brain angiogenesis has been known for many years (10), it is not until recently that neurovascular adaptations in the hippocampus have been associated with cognitive function (29). Exercise enhances the proliferation of brain endothelial cells throughout the brain (113), hippocampal IGF gene expression (47), and serum levels of both IGF (178) and VEGF (63). IGF-1 and VEGF, apparently produced in the periphery, support exercise induced neurogenesis and angiogenesis, as corroborated by blocking the effects of exercise using antibodies against IGF-1 (47) or VEGF (63).
A pair of small hand-weights adds punch to a Pilates workout at home. For this move, imagine you are twirling the weights like sparklers on the Fourth of July. Stand with the weights held at your thighs. Turn them slightly in to face each other and make eight small circles. Each circle should be a little higher until the hands are overhead. Make eight circles in the opposite direction as you lower the arms. Repeat 2-3 times.
Samples were collected in prefrozen 4.5 ml K3 EDTA vacutainer tubes (Becton Dickinson Vacutainer System Europe, Plymouth, UK) and immediately centrifuged at 3000 rpm (Minifuge 2, Heraeus, Germany) for 10 min, and plasma was frozen at −20°C until further analysis. Samples were assayed via RIA for cortisol (DiaSorin, Stillwater, Minnesota, USA), ACTH (Nichols Institute Diagnostics, San Juan Capistrano, California, USA), PRL (Roche Diagnostics, Mannheim, Germany) and GH (Pharmacia & Upjohn Diagnostics, Uppsala, Sweden).
Physical activity is beneficial for young people, who are naturally primed to soak up its rewards. The reality is that the majority of today’s youths, however, fall into one of two camps: Either they are athletes, engaging in one or many sports (as well as auxiliary training such as weightlifting and agility work, which can help create lifelong fitness habits) or they are sedentary.

Both groups performed 2.2 ± 1.3 exercise sessions per week during the year. Walking was the most common exercise type in both groups, but MCT had a higher proportion of walking sessions than HIIT (54.2% vs. 41.1%, p < 0.01). Compared to MCT, HIIT had a higher proportion of sessions with cycling (14.2% vs. 9.8%, p < 0.01), combined endurance and resistance training (10.3% vs. 7.5%, p < 0.01), jogging (6.5% vs. 3.2%, p < 0.01) and swimming (2.6% vs. 1.7%, p < 0.01). Outdoors was the most common exercise location in both training groups (67.8 and 59.1% of all sessions in MCT and HIIT, respectively). Compared to MCT, HIIT had a higher proportion of sessions at a gym (21.4% vs. 17.5%, p < 0.01) and sports facility (9.8% vs. 7.6%, p < 0.01). Both groups performed an equal amount of sessions alone and together with others, but women had a higher proportion of sessions together with others compared to men (56% vs. 44%, p < 0.01).

Choose 10 different exercises - For cardio, focus on exercises with different levels of intensity. For example, you might alternate a high-intensity exercise (such as jumping jacks or burpees) with an easier move (such as marching in place). For strength training, choose compound exercises such as squats, lunges, pushups and dips to work the entire body. Exercise ideas: Step by Step Cardio Exercises, Step by Step Body Weight Exercises
^ Jump up to: a b McKee AC, Daneshvar DH, Alvarez VE, Stein TD (January 2014). "The neuropathology of sport". Acta Neuropathol. 127 (1): 29–51. doi:10.1007/s00401-013-1230-6. PMC 4255282. PMID 24366527. The benefits of regular exercise, physical fitness and sports participation on cardiovascular and brain health are undeniable ... Exercise also enhances psychological health, reduces age-related loss of brain volume, improves cognition, reduces the risk of developing dementia, and impedes neurodegeneration.
(3) Recovery Phase (<60% HRR). Postural control and spine mobility exercises in a quadrupedal position with the platform support, exercises of static balance over either 4 or 2 supports, eyes either open or closed, and with core muscle activation. The latter phase also included various poststretch exercises to restore the preexercise muscle length.
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